ID   A0A2A3H1Q1_9ACTN        Unreviewed;       763 AA.
AC   A0A2A3H1Q1;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=Fe-S oxidoreductase {ECO:0000313|EMBL:PBC62398.1};
GN   ORFNames=BKI49_19350 {ECO:0000313|EMBL:PBC62398.1};
OS   Streptomyces sp. Tue6028.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=2036037 {ECO:0000313|EMBL:PBC62398.1, ECO:0000313|Proteomes:UP000217789};
RN   [1] {ECO:0000313|EMBL:PBC62398.1, ECO:0000313|Proteomes:UP000217789}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tue6028 {ECO:0000313|EMBL:PBC62398.1,
RC   ECO:0000313|Proteomes:UP000217789};
RA   Greule A., Flemming S., Bechthold A.;
RT   "The Draft Genome Sequence of Streptomyces sp. Tue6028 - Producer of
RT   Polyketomycin and Foxicin.";
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PBC62398.1}.
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DR   EMBL; MLCE01000021; PBC62398.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A3H1Q1; -.
DR   Proteomes; UP000217789; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR   InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR   InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR   InterPro; IPR004017; Cys_rich_dom.
DR   InterPro; IPR009051; Helical_ferredxn.
DR   PANTHER; PTHR43255:SF6; IRON-SULFUR-BINDING OXIDOREDUCTASE FADF-RELATED; 1.
DR   PANTHER; PTHR43255; IRON-SULFUR-BINDING OXIDOREDUCTASE FADF-RELATED-RELATED; 1.
DR   Pfam; PF02754; CCG; 2.
DR   Pfam; PF13183; Fer4_8; 1.
DR   SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR   PROSITE; PS00198; 4FE4S_FER_1; 1.
DR   PROSITE; PS51379; 4FE4S_FER_2; 2.
PE   4: Predicted;
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000217789};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        71..92
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        112..134
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        155..174
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        186..202
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        209..230
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          293..323
FT                   /note="4Fe-4S ferredoxin-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51379"
FT   DOMAIN          381..413
FT                   /note="4Fe-4S ferredoxin-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51379"
FT   REGION          736..763
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   763 AA;  83924 MW;  E91B753E994C631F CRC64;
     MQLAAIIVSL VLTVVGVALL ARAIGQFVRY FKLGQPVPAG SRTDNPYQRS VTLVREFLGH
     TRMNRWGIVG VAHWFVAVGF LTLPPTLAQA FGQLFQADWV LPVIGDWLPF EMYTEFIGAM
     TVLGIAVLMV IRLLSLPSRP GRKSRFAGSK AGQAYFVEYV ILTIGLAIYT LRGLEGALHH
     VEGYEAGYFA SYPLVVAFKG LGLSTLQNLV YLVAMIKISV SFIWMIVVSL NTNMGVAWHR
     FLAFPNIWFK REATGGTALG GLQPMTSGGK PIDFTDPGED DVFGVSQVEQ FSWKGLLDFS
     TCTECGRCQS QCPAWNTGKP LSPKLLIMSL RDHAHAKAPY LLAGGGKTME GEEKASEEQL
     KDVPAAALAE AERPLIGTAE ENGVIDPDVL WSCTTCGACV EQCPVDIEHI DHIVDMRRYQ
     VMIESAFPSE AGTMLKNLEK KGNPWGLAKK QRLEWLKELD FEVPVVGKDI EDLTEVEYLY
     WVGCAGALED RAKKTTKAFA ELLNIAGVKF AIMGGDEKCT GDSARRLGNE PLFQELGMEN
     VMALNTAFGE EMDDEGNVTP ESKKPRSAKK IVATCPHCLN TIGNEYPQIG GDYEVIHHTQ
     LLQHLVDEGK LVPVTPVEGI ITYHDPCYLG RHNKIYTPPR EIIGKVPGLR NEEMHRHKER
     GFCCGAGGAR MWMEERIGKR INNERVDEAL SLNPDIVSTA CPFCLVMLTD SVNGKKNDGK
     AKESIQVVDV AQLLLESVRT PVDDEPPAGE AESESEPEPE PVK
//