ID A0A2A3HI41_9ACTN Unreviewed; 456 AA.
AC A0A2A3HI41;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Diaminopimelate decarboxylase {ECO:0000313|EMBL:PBC67382.1};
GN ORFNames=BX265_7975 {ECO:0000313|EMBL:PBC67382.1};
OS Streptomyces sp. TLI_235.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1938860 {ECO:0000313|EMBL:PBC67382.1, ECO:0000313|Proteomes:UP000218662};
RN [1] {ECO:0000313|EMBL:PBC67382.1, ECO:0000313|Proteomes:UP000218662}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TLI_235 {ECO:0000313|EMBL:PBC67382.1,
RC ECO:0000313|Proteomes:UP000218662};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|PIRSR:PIRSR600183-50};
CC -!- SIMILARITY: Belongs to the Orn/Lys/Arg decarboxylase class-II family.
CC {ECO:0000256|RuleBase:RU003737}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PBC67382.1}.
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DR EMBL; NSGV01000004; PBC67382.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A3HI41; -.
DR Proteomes; UP000218662; Unassembled WGS sequence.
DR GO; GO:0016830; F:carbon-carbon lyase activity; IEA:UniProt.
DR Gene3D; 3.20.20.10; Alanine racemase; 1.
DR InterPro; IPR009006; Ala_racemase/Decarboxylase_C.
DR InterPro; IPR022643; De-COase2_C.
DR InterPro; IPR022657; De-COase2_CS.
DR InterPro; IPR022644; De-COase2_N.
DR InterPro; IPR000183; Orn/DAP/Arg_de-COase.
DR InterPro; IPR029066; PLP-binding_barrel.
DR PANTHER; PTHR43727; DIAMINOPIMELATE DECARBOXYLASE; 1.
DR PANTHER; PTHR43727:SF3; DIAMINOPIMELATE DECARBOXYLASE; 1.
DR Pfam; PF02784; Orn_Arg_deC_N; 1.
DR Pfam; PF00278; Orn_DAP_Arg_deC; 1.
DR PRINTS; PR01179; ODADCRBXLASE.
DR SUPFAM; SSF50621; Alanine racemase C-terminal domain-like; 1.
DR SUPFAM; SSF51419; PLP-binding barrel; 1.
DR PROSITE; PS00879; ODR_DC_2_2; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|PIRSR:PIRSR600183-50};
KW Reference proteome {ECO:0000313|Proteomes:UP000218662}.
FT DOMAIN 46..296
FT /note="Orn/DAP/Arg decarboxylase 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02784"
FT DOMAIN 297..391
FT /note="Orn/DAP/Arg decarboxylase 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00278"
FT ACT_SITE 364
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600183-50"
FT MOD_RES 70
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR600183-50"
SQ SEQUENCE 456 AA; 48088 MW; F1337F0649EAE725 CRC64;
MESTHEHEGL RRIDAHRRDR VVRAAAAAGL VGERHVAAGF LDVDGVRRTV ADLHAAFGPD
VPVLHTFAVK AAALVPVLRL VADAGMGCEV ASPGELALAR AAGIPAHRIV LDSPAKTDAE
LAEALGLGVA VNADNLQELE RTAALLAVHR SASVLGLRVN PQVGAGTIGA MSTASEHSKF
GVPLRDPGAR ERVLDAFDRY PWLTRLHVHV GSQGCWPDLI AAGVRATWEL AEEVNRRAGR
RQVTSVDLGG GLPVNFDDDE VRPTHAEYAA HLRAAVPGLF GGDYSLVTEF GRSVVAKHGF
TAARVEYTKE VGGRRIALTH AGAHLATRTV FMPDAWPLRV GVHHPDGTPR RGPEEVQDVA
GPCCFAGDLV ARGRALPRIE PGDLVVLHDT GGYYTSAPWA YNSIARPAVH GFTTAGGQVR
FATVRTEQTL AEIAAEAGGA HADTLTSLAR GGPGGR
//
