ID A0A2A3HQ84_9ACTN Unreviewed; 417 AA.
AC A0A2A3HQ84;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Biotin carboxylase {ECO:0000313|EMBL:PBC70149.1};
GN ORFNames=BX265_7541 {ECO:0000313|EMBL:PBC70149.1};
OS Streptomyces sp. TLI_235.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1938860 {ECO:0000313|EMBL:PBC70149.1, ECO:0000313|Proteomes:UP000218662};
RN [1] {ECO:0000313|EMBL:PBC70149.1, ECO:0000313|Proteomes:UP000218662}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TLI_235 {ECO:0000313|EMBL:PBC70149.1,
RC ECO:0000313|Proteomes:UP000218662};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Purine metabolism. {ECO:0000256|ARBA:ARBA00025704}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PBC70149.1}.
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DR EMBL; NSGV01000003; PBC70149.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A3HQ84; -.
DR OrthoDB; 150319at2; -.
DR Proteomes; UP000218662; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003824; F:catalytic activity; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.20; -; 1.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR InterPro; IPR011761; ATP-grasp.
DR InterPro; IPR003135; ATP-grasp_carboxylate-amine.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR040570; LAL_C2.
DR PANTHER; PTHR43585:SF2; ATP-GRASP ENZYME FSQD; 1.
DR PANTHER; PTHR43585; FUMIPYRROLE BIOSYNTHESIS PROTEIN C; 1.
DR Pfam; PF02222; ATP-grasp; 1.
DR Pfam; PF18603; LAL_C2; 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR PROSITE; PS50975; ATP_GRASP; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00409}; Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00409}; Purine biosynthesis {ECO:0000256|ARBA:ARBA00022755};
KW Reference proteome {ECO:0000313|Proteomes:UP000218662}.
FT DOMAIN 118..314
FT /note="ATP-grasp"
FT /evidence="ECO:0000259|PROSITE:PS50975"
SQ SEQUENCE 417 AA; 44271 MW; CC4C2DE981C1B87E CRC64;
MKFLIINRSK LDTTPYLHWL GDGNEAVLIT AASAVSRAPG AAEAELKGYL EVFVLKDFHE
NPAVETTAIE LHRRHGFDAV IATNEFDLLR AARLRAALGI PGQHPAQAEA YRDKLRMKDL
LSAAGVPVAP YAAVPHATAL HSFAADHGYP VVVKPRRGAG SMGVEVLRDP AELNAYIERT
PALGGDDGAP LMAEKCIEHD LFHIDGLVVD GRPALIWPSA CSSCLGYRDG EVLTSAMLDA
HDPLTGALQD LTVAAMEALG LDDAMAFHAE AFLAPNGDLL LNEIGCRVGG GKIYETVRLG
FGTDMVADHI RALGSVPLAS EPAEAPRQAA GFAIFPGRPG TLTAAPDTCP VDGVDQYRLN
VPVGTVLGRA EHSSARIASV VVRGADRNEV EDVLRKAVDW FESSAVVEPP AEPADRP
//
