ID   A0A2A3HTH2_9ACTN        Unreviewed;       536 AA.
AC   A0A2A3HTH2;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Calcineurin-like phosphoesterase family protein {ECO:0000313|EMBL:PBC71725.1};
GN   ORFNames=BX265_6338 {ECO:0000313|EMBL:PBC71725.1};
OS   Streptomyces sp. TLI_235.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1938860 {ECO:0000313|EMBL:PBC71725.1, ECO:0000313|Proteomes:UP000218662};
RN   [1] {ECO:0000313|EMBL:PBC71725.1, ECO:0000313|Proteomes:UP000218662}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TLI_235 {ECO:0000313|EMBL:PBC71725.1,
RC   ECO:0000313|Proteomes:UP000218662};
RA   Klenk H.-P.;
RT   "Sequencing the genomes of 1000 actinobacteria strains.";
RL   Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PBC71725.1}.
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DR   EMBL; NSGV01000002; PBC71725.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A3HTH2; -.
DR   OrthoDB; 9804511at2; -.
DR   Proteomes; UP000218662; Unassembled WGS sequence.
DR   GO; GO:0003993; F:acid phosphatase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   Gene3D; 3.60.21.10; -; 1.
DR   Gene3D; 2.60.40.380; Purple acid phosphatase-like, N-terminal; 1.
DR   InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR   InterPro; IPR029052; Metallo-depent_PP-like.
DR   InterPro; IPR039331; PPA-like.
DR   InterPro; IPR008963; Purple_acid_Pase-like_N.
DR   InterPro; IPR015914; Purple_acid_Pase_N.
DR   InterPro; IPR006311; TAT_signal.
DR   PANTHER; PTHR22953; ACID PHOSPHATASE RELATED; 1.
DR   PANTHER; PTHR22953:SF154; SLL1064 PROTEIN; 1.
DR   Pfam; PF00149; Metallophos; 1.
DR   Pfam; PF16656; Pur_ac_phosph_N; 1.
DR   SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR   SUPFAM; SSF49363; Purple acid phosphatase, N-terminal domain; 1.
DR   PROSITE; PS51318; TAT; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000218662};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          76..179
FT                   /note="Purple acid phosphatase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16656"
FT   DOMAIN          219..406
FT                   /note="Calcineurin-like phosphoesterase"
FT                   /evidence="ECO:0000259|Pfam:PF00149"
SQ   SEQUENCE   536 AA;  58008 MW;  7C584D144023939C CRC64;
     MDMPNMGVPA GLADRMSTAE QHEYLRSRLS RRRMLRSSAV TVGLLAVGGA LGGGTASAAP
     AAGSTTDGID GALVAPMGRH LAFGPRPDTQ FRISWQVPAP VKRPFLRFGR HPWDLSHKVE
     AEVRALHTPA LTPTGTPVDQ YYLHVALDHL QPDTTYYYGV GHQGFDPASG QAISTLSTFR
     TAPARHGRGG RPYEPFTFTA FGDQGVSSHA AGNDHVILAQ KPAFHLHAGD ICYADPAGSG
     QDSDKSVYSA ATWDAFLAQT ETVAAKIPWM VSYGNHDMEA WYSHHGYGGE DARFFLPGNG
     PDPRTAPGVY SFVYGNVGVV SDANDVSYEI PANLGITAGR QTAWLERTLR SLRADDGVDF
     IVVFFHHCAF STTHQHASEG GVREAWVPLF EKFRVDLVVN GHNHVYERTD AILGNKVAKA
     VPSGGTVEPA RDGAVYVTAG AAGRSLYSFD APDSYEGHEN RRDSVDTYHF AKGGVKVPET
     VEWSRVRYTG YSFVRVDVAP AHRGRTATMK VTALAKDGTR VDHYTIARRA GECATH
//