ID A0A2A3HTL0_9ACTN Unreviewed; 1322 AA.
AC A0A2A3HTL0;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=S-DNA-T family DNA segregation ATPase FtsK/SpoIIIE {ECO:0000313|EMBL:PBC71092.1};
GN ORFNames=BX265_5672 {ECO:0000313|EMBL:PBC71092.1};
OS Streptomyces sp. TLI_235.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1938860 {ECO:0000313|EMBL:PBC71092.1, ECO:0000313|Proteomes:UP000218662};
RN [1] {ECO:0000313|EMBL:PBC71092.1, ECO:0000313|Proteomes:UP000218662}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TLI_235 {ECO:0000313|EMBL:PBC71092.1,
RC ECO:0000313|Proteomes:UP000218662};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PBC71092.1}.
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DR EMBL; NSGV01000002; PBC71092.1; -; Genomic_DNA.
DR Proteomes; UP000218662; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR023836; EccCa-like_Actinobacteria.
DR InterPro; IPR023837; EccCb-like_Actinobacteria.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR03924; T7SS_EccC_a; 1.
DR NCBIfam; TIGR03925; T7SS_EccC_b; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR PANTHER; PTHR22683:SF1; TYPE VII SECRETION SYSTEM PROTEIN ESSC; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 3.
DR SMART; SM00382; AAA; 3.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
DR PROSITE; PS50901; FTSK; 3.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Reference proteome {ECO:0000313|Proteomes:UP000218662};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 37..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 70..90
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 462..661
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT DOMAIN 815..1008
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT DOMAIN 1101..1285
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT REGION 1..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 485..492
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
FT BINDING 834..841
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
FT BINDING 1118..1125
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 1322 AA; 143842 MW; 609340CE886FC1A3 CRC64;
MGVVLIKRKP RRPGPAMPDG EVQLQEPPGL PEKQSGMSSV LTMAPMALGS LSMVFMFLHP
GGTQGGGALS YLAMGMMALS AVGMLLTQLI RGSSDRKQQL RAERRDYLRY LSQMRRQVRH
SIDAQRLALA WRHPAPEELW TLVGTSRLWE RRLTHPDFSD VRIGLGTQRL ATPLAPLATK
PVEDLEPLCA HALRRFIHAY GTVDDQPMAI HLRGFAHVLL RSDDPATARA MLRAVLAQLA
VVHGPDELTV AVVTAVEQRA EWEWTKWLPH ALHPTDTDGA GPVRLVAGSL GEVEQLLGEE
FTGRPGFEPD AAPERDEPFT VVVLDGPGAH TGSRAALAGY RNAVLIDLAD TLEWSPARTT
LRLRIEDGRL TMVGSDSNRK DVVTDLGRPD ALALPAATRL AARLARYRIA DGVDAAEPLA
TDFDLTALLG IADLNTLDVD ALWAQRGIPQ RLRVPLGLGP DGRPVDLDLK ESAQGGMGPH
GMLIGATGSG KSELLRTLVL ALAVTHSSEV LNFVLVDFKG GATFLGLDTL PHTSAVITNL
ADESSLVDRM RDALHGELVR RQELLRDAGY ASLLDHETAR AAGTVLRPLP TLFVVVDEFS
ELLSAHRDFM ELFIMIGRLG RSLGVHLLLA SQRLDEGRMS ALESHLSYRI GLRTFSAMES
RGVLGVPDAY QLPSQPGNGF LRSDISTLTR FKAAYVSGPY RPKRSAARQA AIAGQVVAYG
TDYVMPRRPQ TSPVEPEEEQ GPVGSLLEVA TGRLHDAGPP AHRVWLPPLD VPPTLDELLP
PLVPHPRRGL TTEHAGSHGT LRLPLGVVDR PFQQLRDLLI ADLAGAGGHV GVAGAPQSGK
STLLRSLIAG LALTHTPAEV QFYCLDFGGG TLSTLRSLPH VGGVTGRHDG ERVLRTVAEV
NTVITRRERY FAALGIDSVS DFRRRRAAGD LPEEEQHGDV FLVIDGWNTL RQEFNDLVQP
LTLMSQRGLN YGVHLVIGTT RWGEIAGGLR DQLQTRFELR LGDAVDSVIN MRAATKVPKL
PGRGLTEEQL HFLAALPRID GSGRTDDLGE GIADLVDAVV AHWSGPRAPG VRMLPLSLEA
ERLPAPQGRL RVAIGLEDTE ISPLWHDFEE NPHLLVVGDT ESGKTNLLRL MIDAITTAYT
PSQARIMLVD YRRGLYDAVP EEYRLGYAVA VDKVRQIVDG ASRAMKNRVP PADITPARLR
LRDWWTGPEL FVLVDDYDLV GSGSGSHPFA ALLEYLSQGT EIGLHLVVAR GANGIGRGLA
DPLLRKLQEV NSPALLMSCP PSEGYLFGNF KPRQLATGRG YYITRRRTVQ VQTGHIAEEG
KD
//
