ID A0A2A3HXH7_9ACTN Unreviewed; 730 AA.
AC A0A2A3HXH7;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=DNA helicase IV {ECO:0000313|EMBL:PBC76039.1};
GN ORFNames=BX265_0736 {ECO:0000313|EMBL:PBC76039.1};
OS Streptomyces sp. TLI_235.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1938860 {ECO:0000313|EMBL:PBC76039.1, ECO:0000313|Proteomes:UP000218662};
RN [1] {ECO:0000313|EMBL:PBC76039.1, ECO:0000313|Proteomes:UP000218662}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TLI_235 {ECO:0000313|EMBL:PBC76039.1,
RC ECO:0000313|Proteomes:UP000218662};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PBC76039.1}.
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DR EMBL; NSGV01000001; PBC76039.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A3HXH7; -.
DR Proteomes; UP000218662; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF45; ATP-DEPENDENT DNA HELICASE UVRD2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000218662}.
FT DOMAIN 210..610
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT BINDING 231..238
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 730 AA; 78867 MW; AC4FD051F35D7FCF CRC64;
MRTDLSVNDR CGAPETNSLA MNAFDLPDHL SPKADPALVA ADEQHFAAVA ESLRQAIAEL
SDRLDAVRRA PGGAGRAAMD RDAEVHRLTG RLRALRRFGL DLCLGRVVGA DGSEPVYVGR
LGLTDGTGRR LLVDWRSPAA KPFFAATHAD PMGLASRRRY RWTGGRITDY WDEVFTADGL
EGHAALDDQS AFIAGLGAAR SPRMRDVLAT IQADQDAVIR AGSRGALVVD GGPGTGKTVV
ALHRSAYLLY SDPRLGHRRG GVLFVGPHRP YLDYVADVLP GLGEEGVQTC TLRDLVAEGA
AAGVEADPEA ARLKSSADMV RAIEKAVRFY EEPPSEGTEA GTDWGDLWLS AEDWADAFDA
VEPGTPHNEA RAQILEELAA ILLGRLDEDV APELVRRALL RDEELVATLN RAWPLIEAAD
LVGDLWSVPA YLRMCAPWLG PDDVRRLRRP DAQAWTVSDL PLLDAARHRL GDPEAARHRR
RQEVAVAAER ARMADVIGDI LRADDDGEGA VAMLRGRDLQ DTLVDGAALP GTDPEPLAGP
FAHIVVDEAQ ELTDAEWQML LLRCPSRSFT VVGDRAQARH GFTESWRERL ERIGLDRIEV
ASLGINYRTP AEVMAEAAPV VRAVLPDANV PTSVRSSGIP VVHGSVEDLD AVLERWLAAH
ADGTACVIGA PGFRATPRVR SLTPALSKGL EFDLVVLVDP ETFGEGVAGA VDRYVAMTRT
TRQLVVLRSS
//
