ID A0A2A3I932_9ACTN Unreviewed; 423 AA.
AC A0A2A3I932;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=DNA (cytosine-5-)-methyltransferase {ECO:0000256|ARBA:ARBA00011975};
DE EC=2.1.1.37 {ECO:0000256|ARBA:ARBA00011975};
GN ORFNames=BX265_4987 {ECO:0000313|EMBL:PBC80151.1};
OS Streptomyces sp. TLI_235.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1938860 {ECO:0000313|EMBL:PBC80151.1, ECO:0000313|Proteomes:UP000218662};
RN [1] {ECO:0000313|EMBL:PBC80151.1, ECO:0000313|Proteomes:UP000218662}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TLI_235 {ECO:0000313|EMBL:PBC80151.1,
RC ECO:0000313|Proteomes:UP000218662};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. C5-methyltransferase family. {ECO:0000256|PROSITE-
CC ProRule:PRU01016}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PBC80151.1}.
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DR EMBL; NSGV01000001; PBC80151.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A3I932; -.
DR OrthoDB; 9813719at2; -.
DR Proteomes; UP000218662; Unassembled WGS sequence.
DR GO; GO:0003886; F:DNA (cytosine-5-)-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0009307; P:DNA restriction-modification system; IEA:UniProtKB-KW.
DR Gene3D; 3.90.120.10; DNA Methylase, subunit A, domain 2; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR001525; C5_MeTfrase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR10629; CYTOSINE-SPECIFIC METHYLTRANSFERASE; 1.
DR PANTHER; PTHR10629:SF52; DNA (CYTOSINE-5)-METHYLTRANSFERASE 1; 1.
DR Pfam; PF00145; DNA_methylase; 2.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51679; SAM_MT_C5; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW ProRule:PRU01016}; Reference proteome {ECO:0000313|Proteomes:UP000218662};
KW Restriction system {ECO:0000256|ARBA:ARBA00022747};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU01016};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU01016}.
FT ACT_SITE 80
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01016"
SQ SEQUENCE 423 AA; 46517 MW; 300A725E693E3EEB CRC64;
MTFRFDGDLD FTDLFCGGGG SSTGLTETGY TLRLAANHDP VSIRTHAANH PTAEHLCADI
NLLDKRRLPK TRVLWGSPIC TEISPSGGRK RTRGQTVLDL GDGAAAEDTF ARTRATALDV
IAAAEVHRYD AVLVENVIEF ALDWELFDWW LSGWKVLGYN HQIVCASSAH LGGGDNELAP
QDRNRLYIAF TREGIPLPDL EVRPAALCPT CGPVQARQVW RNPSRRRIGK WGVQYDYRCP
NRSCGHLILD PTVRPVADII DWDLPGTRVG DGRPDRKAFT PYAATTRARI AIGLDRFGHE
PHVAVLRRNG TAVGTTGTIP ALSAQGRHHA LVVPNGRKGL PRTTNEPMTT IATKPHHSLV
RTAPTVDDCT LRMFTTRELM QAQRFPKDYI VHGNQAEQIL QAGNAVSVNA ARWLGERVKA
VLA
//
