ID A0A2A3K1P7_9RHOB Unreviewed; 693 AA.
AC A0A2A3K1P7;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN ORFNames=CLG85_02575 {ECO:0000313|EMBL:PBD20694.1};
OS Alloyangia mangrovi.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Alloyangia.
OX NCBI_TaxID=1779329 {ECO:0000313|EMBL:PBD20694.1};
RN [1] {ECO:0000313|EMBL:PBD20694.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SAOS 153D {ECO:0000313|EMBL:PBD20694.1};
RA Verma A., Krishnamurthi S.;
RT "Yangia sp. SAOS 153D whole genome sequencing.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- SIMILARITY: Belongs to the helicase family. UvrD subfamily.
CC {ECO:0000256|ARBA:ARBA00009922}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PBD20694.1}.
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DR EMBL; NTHN01000026; PBD20694.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A3K1P7; -.
DR OrthoDB; 9806690at2; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR CDD; cd17932; DEXQc_UvrD; 1.
DR Gene3D; 1.10.10.160; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR013986; DExx_box_DNA_helicase_dom_sf.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF3; ATP-DEPENDENT HELICASE_DEOXYRIBONUCLEASE SUBUNIT B; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}.
FT DOMAIN 27..318
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT DOMAIN 319..578
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51217"
FT BINDING 48..55
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 693 AA; 75714 MW; B098C3D822EFC6AE CRC64;
MTQVEITAGK AAGQADPLAA LNANQRAAAT FGVRPGDAAP SGPLLVIAGA GSGKTSTLAH
RVAHLLMNGA DPQRILLMTF SRRAATELTR RVEAITTRAM GTGIVAEALT WAGTFHAVGA
RLLREHAPAI GLNPEFSIHD REDSADLMNL CRNGLGLSQT ETRFPAKGTC LSIYSRAVNA
GEPLAEVLRD HFPWCAMWEA ELKALFGAYV RAKQDQNVLD YDDLLLAWAQ VMSDAEFAAH
IGSAWDHVLI DEYQDTNRLQ ARILMALKPD GRGLTVVGDD AQSIYAFRAA TVRNILDFPA
AFAPPADVIT LDRNYRSTAP ILEAANAVIG QARERFTKNL WTTRASAEKP RLVTVSTEAD
QARYMVDRIL EDRETGTTLK QQAVLFRTSS HSVQLEAELT RRNVPYVKFG GLKFLDSAHV
KDLLSVLRLA RNPRDRVAGF RVLQLIPGIG PKSAANILDA LDLSPDPAAA LNDVAPPAKA
EADWPGFVAA MTTRAPWPAA ISLARAWYEP HLTRIHEDAD TRRGDLLQLE QIALGYPSAE
AFLTELTLEP PDATSDRSGV PLKDEDYLIL STIHSAKGQE WKSVYLLNAV DGCIPSDLGT
GSTPELEEER RLLYVAMTRA KDRLTLGLPL RFYVTQQSRG GDRHVYATRT RFIPRELLGH
FESLHWSPAP QGGTPAPAPG RIDIAAQMRD MWG
//
