ID A0A2A3U7W1_9SPHI Unreviewed; 277 AA.
AC A0A2A3U7W1;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 13.
DE SubName: Full=Mechanosensitive ion channel protein MscS {ECO:0000313|EMBL:PBQ31057.1};
GN ORFNames=CNR22_04495 {ECO:0000313|EMBL:PBQ31057.1};
OS Sphingobacteriaceae bacterium.
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae.
OX NCBI_TaxID=2021370 {ECO:0000313|EMBL:PBQ31057.1, ECO:0000313|Proteomes:UP000217505};
RN [1] {ECO:0000313|EMBL:PBQ31057.1, ECO:0000313|Proteomes:UP000217505}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SH-48 {ECO:0000313|EMBL:PBQ31057.1,
RC ECO:0000313|Proteomes:UP000217505};
RA Choi A.;
RT "Draft genome sequence of sphingobacterial strain SH-48, isolated from
RT freshwater in Korea.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|ARBA:ARBA00008017}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PBQ31057.1}.
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DR EMBL; NVQB01000001; PBQ31057.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A3U7W1; -.
DR OrthoDB; 9809206at2; -.
DR Proteomes; UP000217505; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008381; F:mechanosensitive monoatomic ion channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR045275; MscS_archaea/bacteria_type.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR011014; MscS_channel_TM-2.
DR PANTHER; PTHR30221; SMALL-CONDUCTANCE MECHANOSENSITIVE CHANNEL; 1.
DR PANTHER; PTHR30221:SF1; SMALL-CONDUCTANCE MECHANOSENSITIVE CHANNEL; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR SUPFAM; SSF82861; Mechanosensitive channel protein MscS (YggB), transmembrane region; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000217505};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 31..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 118..176
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
SQ SEQUENCE 277 AA; 30779 MW; DB798AC6D3013C1A CRC64;
MSDFKFLVTL ERFLNNFHFS WNAFLSHVPE ILGGILCFTL TLFLANFLSK LASTYAVRRS
KDILIANFVG KIIWTVIFIF GTVLALGILG LGNVSNKILA GAGITTFVVG FALKDIGENF
LSGIILAFSR PYHVGNLIEC TGVKGIVKDM TMRQTTVEAE NGKIIMIPNS AILKNPLTRY
LNDDNNLRQE FSISIESSKL QEAVILIKKT VSNFQYVMNE ERPVKVVVDS ISGDKIKMLV
IYWFSAKAFH GSRSGSKSEI MMAVIMKLNE AEVKFSG
//
