ID   A0A2A3XI37_9GAMM        Unreviewed;       951 AA.
AC   A0A2A3XI37;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   SubName: Full=GGDEF domain-containing protein {ECO:0000313|EMBL:PCC23844.1};
GN   ORFNames=CIK78_07895 {ECO:0000313|EMBL:PCC23844.1};
OS   Halomonas sp. JB37.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC   Halomonadaceae; Halomonas.
OX   NCBI_TaxID=2024405 {ECO:0000313|EMBL:PCC23844.1, ECO:0000313|Proteomes:UP000217454};
RN   [1] {ECO:0000313|EMBL:PCC23844.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JB37 {ECO:0000313|EMBL:PCC23844.1};
RX   PubMed=28644126;
RA   Bonham K.S., Wolfe B.E., Dutton R.J.;
RT   "Extensive horizontal gene transfer in cheese-associated bacteria.";
RL   Elife 6:e22144-e22144(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PCC23844.1}.
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DR   EMBL; NRGW01000001; PCC23844.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A3XI37; -.
DR   OrthoDB; 9787514at2; -.
DR   Proteomes; UP000217454; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR029150; dCache_3.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013767; PAS_fold.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR33121:SF23; CYCLIC DI-GMP PHOSPHODIESTERASE PDEB; 1.
DR   PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR   Pfam; PF14827; dCache_3; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF00989; PAS; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00091; PAS; 1.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        307..327
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          404..456
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          552..685
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          696..947
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
SQ   SEQUENCE   951 AA;  105901 MW;  98A152C064F69CD7 CRC64;
     MKTTVPIHKS HRFSLTWRVI TLSSLLLLAL VTLFTVLGHD NLTRQFKESR DQHHERQQRE
     IRLALQHSSE NLRQLAGLTA ASSSLGPPLQ AGDSETVGQA LNSQWPALQL EAGIDEVLVM
     DTHGQVLGSW GMGASESQLP ILSWVRRVIN TEIPLTTLRC STSCQQFAAV PVLVEGESVG
     MLVLTRSLAD VTREANEVSG SEVALVVTGA DDQRDIADER YLERWNGRIT ALTRQEYSLA
     LLQQAAQTLS LPSLLEAPAI FENEGRSLEL SAVDMEEDAD LIHSSYFLLI SDITEQIDTI
     NQDTRTLLFV GVIGWILAEL LLLFILLGPM ARLRRVAGLL PTLARGKFSD IRSAIPERQR
     RLPDEIDVLE STTLALSHQL EMLETQVQER GEQLAERIEE LAKERDFVNS LLNTAQVFIV
     AQDSTGRISL VNEYSQEILG LDESSLLGRN FGDIFENGSS KLFHTPNVSQ QDEKTLLTPD
     QSLHTIAWYH APLQAGSNEQ PSRISVGLDI TKRKAAEARL TWLAERDPLT ELYNRRYFQN
     SLQAAMERTM HANGAVLLLD LDQFKEINEL SGHHVGDQLL RKVAKTLFHN LGRHGVVARL
     GGDEFALLLE DTNAEQSVKI AQYIVQLLEN LGFTAGERRH RVTASIGIAL FPMHGHTPAD
     MMASADVAMY KAKENGLQHW HLLSQAENAK DELKERVYWV ERIRNALEEN SFELMVQPIM
     RLEDSDVKHH EVLLRMRDID GSLISPAHFI PVAEQSGQIV LIDRWVLRQS LKALSQLQKR
     GITLAVNLSG QSLHDEELKQ YLSDELAASG ADPHHLILEV TETVAVTDFS TARGVLQSVR
     ELGCRIALDD FGIGFSSLHY LGQLPIDYIK IDGSFIHSLL TNPDSRVIVR AIADIAKGFG
     KQTIAEFVDQ EALLPLLKSY GITYGQGFYL GQPVAIGNAF SDLPPSDKYL N
//