ID A0A2A3Y3F0_9MICC Unreviewed; 398 AA.
AC A0A2A3Y3F0;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=galactokinase {ECO:0000256|ARBA:ARBA00012315};
DE EC=2.7.1.6 {ECO:0000256|ARBA:ARBA00012315};
DE AltName: Full=Galactose kinase {ECO:0000256|ARBA:ARBA00029590};
GN Name=galK {ECO:0000313|EMBL:PCC30480.1};
GN ORFNames=CIK76_00315 {ECO:0000313|EMBL:PCC30480.1};
OS Glutamicibacter sp. BW80.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Glutamicibacter.
OX NCBI_TaxID=2024404 {ECO:0000313|EMBL:PCC30480.1, ECO:0000313|Proteomes:UP000218725};
RN [1] {ECO:0000313|EMBL:PCC30480.1, ECO:0000313|Proteomes:UP000218725}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BW80 {ECO:0000313|EMBL:PCC30480.1,
RC ECO:0000313|Proteomes:UP000218725};
RX PubMed=28644126;
RA Bonham K.S., Wolfe B.E., Dutton R.J.;
RT "Extensive horizontal gene transfer in cheese-associated bacteria.";
RL Elife 6:e22144-e22144(2017).
CC -!- PATHWAY: Carbohydrate metabolism; galactose metabolism.
CC {ECO:0000256|ARBA:ARBA00004947}.
CC -!- SIMILARITY: Belongs to the GHMP kinase family. GalK subfamily.
CC {ECO:0000256|ARBA:ARBA00006566}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PCC30480.1}.
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DR EMBL; NRGV01000001; PCC30480.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A3Y3F0; -.
DR Proteomes; UP000218725; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004335; F:galactokinase activity; IEA:InterPro.
DR GO; GO:0006012; P:galactose metabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.890; GHMP kinase, C-terminal domain; 1.
DR InterPro; IPR000705; Galactokinase.
DR InterPro; IPR019741; Galactokinase_CS.
DR InterPro; IPR019539; GalKase_N.
DR InterPro; IPR013750; GHMP_kinase_C_dom.
DR InterPro; IPR036554; GHMP_kinase_C_sf.
DR InterPro; IPR006204; GHMP_kinase_N_dom.
DR InterPro; IPR006206; Mevalonate/galactokinase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR NCBIfam; TIGR00131; gal_kin; 1.
DR PANTHER; PTHR10457:SF35; GALACTOKINASE; 1.
DR PANTHER; PTHR10457; MEVALONATE KINASE/GALACTOKINASE; 1.
DR Pfam; PF10509; GalKase_gal_bdg; 1.
DR Pfam; PF08544; GHMP_kinases_C; 1.
DR Pfam; PF00288; GHMP_kinases_N; 1.
DR PIRSF; PIRSF000530; Galactokinase; 1.
DR PRINTS; PR00473; GALCTOKINASE.
DR PRINTS; PR00959; MEVGALKINASE.
DR SUPFAM; SSF55060; GHMP Kinase, C-terminal domain; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR PROSITE; PS00106; GALACTOKINASE; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Galactose metabolism {ECO:0000256|ARBA:ARBA00023144};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:PCC30480.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transferase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:PCC30480.1}.
FT DOMAIN 18..67
FT /note="Galactokinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF10509"
FT DOMAIN 132..198
FT /note="GHMP kinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00288"
FT DOMAIN 299..377
FT /note="GHMP kinase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08544"
SQ SEQUENCE 398 AA; 42900 MW; 11BB36D28D3DFFE2 CRC64;
MSISDSKETT QRMAALHQKF AKIYGHQPEG IWRAPGRVNL IGEHTDYNMG FVLPFAIDKN
ALVAVRRKTQ LDADRQTLDF ASTYGSGEHP PITSITFDEL VPRAVPGWAA YPAAVLWALN
QLDGVELGGI QLLVDSDVPV GSGLSSSHAL EVATIVALDD LYELGLSKVQ MAQLTQRAEN
EFVGAPTGIM DQSASLMSHA QHALFLDCRS METQAVPLPL AQHDAVVLVM DTRVEHSHVD
GGYAARRASC EQAAAALEVQ SLREVTVVAE LEAIEDPVAK RRAMHIVTEN RRVLDTVFAL
REGDLEAVGK LLYQSHESMR DDYEISSEEL DVAVEAAMAA GAIGARMTGG GFGGSAIALI
KREHIDKVSQ AVREAFDQAG YVEPAIFTVI ADEGAGKA
//
