ID A0A2A3Y8T5_9MICC Unreviewed; 316 AA.
AC A0A2A3Y8T5;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=[ribosomal protein S5]-alanine N-acetyltransferase {ECO:0000256|ARBA:ARBA00039124};
DE EC=2.3.1.267 {ECO:0000256|ARBA:ARBA00039124};
GN ORFNames=CIK74_09625 {ECO:0000313|EMBL:PCC34541.1};
OS Glutamicibacter sp. BW77.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Glutamicibacter.
OX NCBI_TaxID=2024402 {ECO:0000313|EMBL:PCC34541.1, ECO:0000313|Proteomes:UP000218926};
RN [1] {ECO:0000313|EMBL:PCC34541.1, ECO:0000313|Proteomes:UP000218926}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BW77 {ECO:0000313|EMBL:PCC34541.1,
RC ECO:0000313|Proteomes:UP000218926};
RX PubMed=28644126;
RA Bonham K.S., Wolfe B.E., Dutton R.J.;
RT "Extensive horizontal gene transfer in cheese-associated bacteria.";
RL Elife 6:e22144-e22144(2017).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + N-terminal L-alanyl-[ribosomal protein uS5] = CoA
CC + H(+) + N-terminal N(alpha)-acetyl-L-alanyl-[ribosomal protein uS5];
CC Xref=Rhea:RHEA:43752, Rhea:RHEA-COMP:10672, Rhea:RHEA-COMP:10673,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:57287, ChEBI:CHEBI:57288,
CC ChEBI:CHEBI:64718, ChEBI:CHEBI:83683; EC=2.3.1.267;
CC Evidence={ECO:0000256|ARBA:ARBA00036822};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the acetyltransferase family. RimJ subfamily.
CC {ECO:0000256|ARBA:ARBA00038502}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PCC34541.1}.
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DR EMBL; NRGT01000060; PCC34541.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A3Y8T5; -.
DR OrthoDB; 2061990at2; -.
DR Proteomes; UP000218926; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR Gene3D; 3.10.450.50; -; 1.
DR Gene3D; 3.40.630.30; -; 1.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR027843; DUF4440.
DR InterPro; IPR000182; GNAT_dom.
DR InterPro; IPR032710; NTF2-like_dom_sf.
DR PANTHER; PTHR43792:SF8; [RIBOSOMAL PROTEIN S5]-ALANINE N-ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR43792; GNAT FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00765)-RELATED-RELATED; 1.
DR Pfam; PF13302; Acetyltransf_3; 1.
DR Pfam; PF14534; DUF4440; 1.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR SUPFAM; SSF54427; NTF2-like; 1.
DR PROSITE; PS51186; GNAT; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000218926};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 146..304
FT /note="N-acetyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS51186"
SQ SEQUENCE 316 AA; 35336 MW; 6F340025F6BDBC30 CRC64;
MPEFSVPGDL SPDHLVAAKI IDGEKQLLTQ RIRHNQQELK RLLHEDFEEV GASGRNYDRS
QIIKLLMAEP VDQSPTFQLL EPRIQQLSET LVLLRWKTGA DTPSQRTSLW IHSAHGWQLL
FHQGTKLPKF PADVATSPYV ASEAQAFVRP LRPSDAPQVL EAFCSHPDMA RQGEVKNLVE
AENYIQQLLK NPDQQVPLAI VQGTGLVGLV SASIDSGNRN AWVWYWMHAA HRGSGLASRA
LAALADELFT AHQIHRLELG LRVNNPASKK VAERCGFVLE GRERDKFLIN GERIDVLNYA
RLITDQAPPI TALALH
//
