ID A0A2A3YLP9_9MICO Unreviewed; 369 AA.
AC A0A2A3YLP9;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Lipoate--protein ligase {ECO:0000313|EMBL:PCC40223.1};
GN ORFNames=CIK66_06265 {ECO:0000313|EMBL:PCC40223.1};
OS Brachybacterium alimentarium.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Dermabacteraceae;
OC Brachybacterium.
OX NCBI_TaxID=47845 {ECO:0000313|EMBL:PCC40223.1, ECO:0000313|Proteomes:UP000218598};
RN [1] {ECO:0000313|EMBL:PCC40223.1, ECO:0000313|Proteomes:UP000218598}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=341_9 {ECO:0000313|EMBL:PCC40223.1,
RC ECO:0000313|Proteomes:UP000218598};
RX PubMed=28644126;
RA Bonham K.S., Wolfe B.E., Dutton R.J.;
RT "Extensive horizontal gene transfer in cheese-associated bacteria.";
RL Elife 6:e22144-e22144(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PCC40223.1}.
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DR EMBL; NRGR01000008; PCC40223.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A3YLP9; -.
DR OrthoDB; 9788148at2; -.
DR Proteomes; UP000218598; Unassembled WGS sequence.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR CDD; cd16443; LplA; 1.
DR Gene3D; 3.30.390.50; CO dehydrogenase flavoprotein, C-terminal domain; 1.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR004143; BPL_LPL_catalytic.
DR PANTHER; PTHR43679:SF4; LIPOATE--PROTEIN LIGASE; 1.
DR PANTHER; PTHR43679; OCTANOYLTRANSFERASE LIPM-RELATED; 1.
DR Pfam; PF03099; BPL_LplA_LipB; 1.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR PROSITE; PS51733; BPL_LPL_CATALYTIC; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:PCC40223.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000218598}.
FT DOMAIN 148..340
FT /note="BPL/LPL catalytic"
FT /evidence="ECO:0000259|PROSITE:PS51733"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 369 AA; 40697 MW; C742DBC43BF201ED CRC64;
MAETNENTNQ HPNENTVMHG EYKVRGGKLV AVDVTVQDDR IATAHVFGDF FLEPDDALEE
LNAALNGMAT EATAAELASA LTTRIESLPY PVQLIGFDAE AVAIATRRAL GHASSWDDLT
FDVIGPQVLP PVMHVALDEV LPLEVIAGRR RPHFRIWDWD TPLVVIGSYQ SVRNEIDAEG
AAKHDIGVVR RITGGGAMFM EHGNCITYSL VVPTSLVEGL SFEQAYAYLD DWVMGALAEI
GVKARYVPLN DIASEQGKIG GAAQRRFAGG VLLHHVTMSY DIDADKMGEV LRIGREKLSD
KGTRSANKRV DPIRSQTGLP RDQIIEGFLD YFRSRYDTVD SGYTEDELTK ARELVATKFS
TEEWTHRVP
//
