ID A0A2A3YP20_9MICO Unreviewed; 340 AA.
AC A0A2A3YP20;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 13.
DE SubName: Full=NADP-dependent oxidoreductase {ECO:0000313|EMBL:PCC40845.1};
GN ORFNames=CIK66_00975 {ECO:0000313|EMBL:PCC40845.1};
OS Brachybacterium alimentarium.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Dermabacteraceae;
OC Brachybacterium.
OX NCBI_TaxID=47845 {ECO:0000313|EMBL:PCC40845.1, ECO:0000313|Proteomes:UP000218598};
RN [1] {ECO:0000313|EMBL:PCC40845.1, ECO:0000313|Proteomes:UP000218598}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=341_9 {ECO:0000313|EMBL:PCC40845.1,
RC ECO:0000313|Proteomes:UP000218598};
RX PubMed=28644126;
RA Bonham K.S., Wolfe B.E., Dutton R.J.;
RT "Extensive horizontal gene transfer in cheese-associated bacteria.";
RL Elife 6:e22144-e22144(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PCC40845.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NRGR01000004; PCC40845.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A3YP20; -.
DR OrthoDB; 9805663at2; -.
DR Proteomes; UP000218598; Unassembled WGS sequence.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd05288; PGDH; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR041694; ADH_N_2.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR045010; MDR_fam.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR43205; PROSTAGLANDIN REDUCTASE; 1.
DR PANTHER; PTHR43205:SF7; PROSTAGLANDIN REDUCTASE 1; 1.
DR Pfam; PF16884; ADH_N_2; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000218598}.
FT DOMAIN 18..337
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 340 AA; 35748 MW; 27EA7EA7CF900E4B CRC64;
MSSTVLNHRI RLGSRPHGEP TADDYLHDAV EVSSPAAGQV LLRTHYISLD PYVRGRMSSA
KSYAAPMEVG DVIEGGTVSE VVESAADGFA PGDMVLSYGG WQEYSLESAD GLRRLDPSVA
PVTTALGVLG MPGFTAYAGL LAIGRPQPGE TVAVAAATGP VGSAVGQIAR IHGAKAVGIA
GGERKVGQLR EYGFDEALDH RAPDLPGRLA QATPDGIDVY FENVGGAVWD AVLPQLNTYA
RVPVCGLVSG YNSTSLPEGP DRSGQLMGTV LSKSLTLRGF IQLEFVSSMF EDFLRDMSGW
VASGQVQHTE DITEGLDRAP EAFAGMLRGQ NFGKALVKVS
//
