ID A0A2A4FTR1_9SPHN Unreviewed; 395 AA.
AC A0A2A4FTR1;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Glutathione-dependent formaldehyde dehydrogenase {ECO:0000313|EMBL:PCE41084.1};
GN ORFNames=COO09_17210 {ECO:0000313|EMBL:PCE41084.1};
OS Rhizorhabdus dicambivorans.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Rhizorhabdus.
OX NCBI_TaxID=1850238 {ECO:0000313|EMBL:PCE41084.1, ECO:0000313|Proteomes:UP000218934};
RN [1] {ECO:0000313|EMBL:PCE41084.1, ECO:0000313|Proteomes:UP000218934}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ndbn-20m {ECO:0000313|EMBL:PCE41084.1,
RC ECO:0000313|Proteomes:UP000218934};
RA Na L.;
RT "The Catabolism of 3,6-Dichlorosalicylic acid is Initiated by the
RT Cytochrome P450 Monooxygenase DsmABC in Rhizorhabdus dicambivorans
RT Ndbn-20.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947,
CC ECO:0000256|RuleBase:RU361277};
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|RuleBase:RU361277}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PCE41084.1}.
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DR EMBL; NWUF01000019; PCE41084.1; -; Genomic_DNA.
DR RefSeq; WP_066966282.1; NZ_NWUF01000019.1.
DR AlphaFoldDB; A0A2A4FTR1; -.
DR KEGG; rdi:CMV14_20110; -.
DR OrthoDB; 9773078at2; -.
DR Proteomes; UP000218934; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd08283; FDH_like_1; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR42813:SF2; DEHYDROGENASE, ZINC-CONTAINING, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02810)-RELATED; 1.
DR PANTHER; PTHR42813; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU361277};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000218934};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU361277}.
FT DOMAIN 26..150
FT /note="Alcohol dehydrogenase-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08240"
FT DOMAIN 197..265
FT /note="Alcohol dehydrogenase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00107"
SQ SEQUENCE 395 AA; 43035 MW; 438D42737A9118A5 CRC64;
MRALTWHGKH DVRVDTVDDP EILNPRDAII RITSTAICGS DLHLYDGYIP TMQKGDILGH
EFMGEVVETG SASTLKKGQR VVVPFTISCG GCFHCGKHQY SACDNGNPAD NQDIAMELYG
QPMSGLFGYS HMTGGYAGGQ AEYVRVPFSD VGPIVIPDGI EDDKVLFLSD ILPTGWMAAE
NADIEPGDTV AVWGCGPVGL FAVQSAFLMG AERVIAIDHF PHRLELARRF GAETVNFEES
KTYEALMEMT GGIGPDAVID AVGLEAHGFF VDNVIDQIKA STFLGTDRPH AIRQAIIACR
KGGRVSMPAV YGGFVDKFPL GAFMQKGLTL KTGQTHVQHY MPGLLNAILE DKIDTTFLIS
HRMPLEQAAE GYRMFHDKQD EVTKIVLKPG MTTTH
//
