ID A0A2A4FWW4_9SPHN Unreviewed; 985 AA.
AC A0A2A4FWW4;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Sarcosine oxidase subunit alpha family protein {ECO:0000313|EMBL:PCE43286.1};
GN ORFNames=COO09_05810 {ECO:0000313|EMBL:PCE43286.1};
OS Rhizorhabdus dicambivorans.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Rhizorhabdus.
OX NCBI_TaxID=1850238 {ECO:0000313|EMBL:PCE43286.1, ECO:0000313|Proteomes:UP000218934};
RN [1] {ECO:0000313|EMBL:PCE43286.1, ECO:0000313|Proteomes:UP000218934}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ndbn-20m {ECO:0000313|EMBL:PCE43286.1,
RC ECO:0000313|Proteomes:UP000218934};
RA Na L.;
RT "The Catabolism of 3,6-Dichlorosalicylic acid is Initiated by the
RT Cytochrome P450 Monooxygenase DsmABC in Rhizorhabdus dicambivorans
RT Ndbn-20.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PCE43286.1}.
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DR EMBL; NWUF01000004; PCE43286.1; -; Genomic_DNA.
DR RefSeq; WP_066969094.1; NZ_NWUF01000004.1.
DR AlphaFoldDB; A0A2A4FWW4; -.
DR KEGG; rdi:CMV14_00775; -.
DR OrthoDB; 5287468at2; -.
DR Proteomes; UP000218934; Unassembled WGS sequence.
DR GO; GO:0008115; F:sarcosine oxidase activity; IEA:InterPro.
DR GO; GO:0046653; P:tetrahydrofolate metabolic process; IEA:InterPro.
DR Gene3D; 3.10.20.440; 2Fe-2S iron-sulphur cluster binding domain, sarcosine oxidase, alpha subunit, N-terminal domain; 1.
DR Gene3D; 1.10.10.1100; BFD-like [2Fe-2S]-binding domain; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR042204; 2Fe-2S-bd_N.
DR InterPro; IPR041854; BFD-like_2Fe2S-bd_dom_sf.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR028896; GCST/YgfZ/DmdA.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR006277; Sarcosine_oxidase_asu.
DR InterPro; IPR041117; SoxA_A3.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR NCBIfam; TIGR01372; soxA; 1.
DR PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR Pfam; PF13510; Fer2_4; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR Pfam; PF17806; SO_alpha_A3; 1.
DR PIRSF; PIRSF037980; SoxA; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00469; PNDRDTASEII.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000218934}.
FT DOMAIN 168..413
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
FT DOMAIN 502..585
FT /note="SoxA A3"
FT /evidence="ECO:0000259|Pfam:PF17806"
FT DOMAIN 601..864
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 891..977
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 985 AA; 105400 MW; F73E32DF1F3AB767 CRC64;
MSRLASGGLI DRSRTLDFSF DGRRYSGFAG DTLASALIAN NVRLVGRSFK YHRPRGILTA
GSEEPNALVT LGSGAEAEPN SRATTITLFD GLRATSQNRW PSLSFDLLSV NQLAAPIFVA
GFYYKTFMWP AALWEKLYEP LIRRAAGLGA LSGLPDPSSY DRNHGFCDLL VIGGGVAGIA
AALVAGRAGL RVIIANEDAR LGGRLLAERH EVDGVAAAEW AADQAAELAS MPNVTVLDRT
TVFGAYDGRE YGAVERLTDH LPNQDRRGPR QRLWKIVARR ALLATGAIER PLVFGGNDRP
GVMMASAVST YVNRHAALPG RRAVLFTTTD SGWRTAEDLM LAGADIAAVV NPRGEAGGAA
DRLRAAGIRI LQGAMVTNAR GAPLKAVDIR TSDGGTVTVK ADLLAMSGGW NPAIGIGSNL
GARPVWSDRI DSFLLEDAPP GLAATGAAAG ELSLAAALAD GVAKAGGVVE DLGFKAVAFP
IPPTSDDSGR AAPLWHVGEH GGKAFVDFQH DVTDSDVSLA AREGFVSIEH LKRYTTLGMA
TDQGKTSQLN GHALLAAATG RSLAETGTIL SRPPYLPVAI GVLAGHHRDE HFRPERRTAS
HEWAARRNAV FVDAGQWKRA QWYPLPGEGD WLESVSREVR ATRENVGICD VSTLGKIDVQ
GRDAGTLLDR LYINMFSTLP IGKARYGVML REDGFVMDDG TTTRLAEDRF FVTTTTVNAA
KVMQHIDYAR QILWPELDVQ ATSVTEQWAT YAVAGPRSRD LLQRLLPDQD ISNEALPFMG
AREFRWRGVT ARLFRLSFSG ELAYEIAVPA THGELLIHAL FEAGEAFGVT PYGTEALGVM
RIEKGHAAGN ELNGQTTAWD LGMGGMMSRK KDFIGRVLGN RPALSDPSRP RLVGVRPLTL
GDKVRAGAHL LPAGAAAVAA NDQGHVSSAA WSPSLGHWIG LALLRNGPER IGEEMVMHDP
VRGADIAVEI CHPVFIDPEG ARVRG
//
