ID A0A2A4IBZ8_9SPHN Unreviewed; 347 AA.
AC A0A2A4IBZ8;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=3-hydroxyisobutyryl-CoA hydrolase {ECO:0000256|ARBA:ARBA00011915};
DE EC=3.1.2.4 {ECO:0000256|ARBA:ARBA00011915};
GN ORFNames=COA07_07430 {ECO:0000313|EMBL:PCG15340.1};
OS Sphingomonas adhaesiva.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingomonas.
OX NCBI_TaxID=28212 {ECO:0000313|EMBL:PCG15340.1, ECO:0000313|Proteomes:UP000218323};
RN [1] {ECO:0000313|EMBL:PCG15340.1, ECO:0000313|Proteomes:UP000218323}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 7418 {ECO:0000313|EMBL:PCG15340.1,
RC ECO:0000313|Proteomes:UP000218323};
RA Feng G., Zhu H.;
RT "Sphingomonas adhaesiva DSM 7418, whole genome shotgun sequence.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-
CC methylpropanoate + CoA + H(+); Xref=Rhea:RHEA:20888,
CC ChEBI:CHEBI:11805, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57340; EC=3.1.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001709};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PCG15340.1}.
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DR EMBL; NWVC01000002; PCG15340.1; -; Genomic_DNA.
DR RefSeq; WP_066712401.1; NZ_NWVC01000002.1.
DR AlphaFoldDB; A0A2A4IBZ8; -.
DR Proteomes; UP000218323; Unassembled WGS sequence.
DR GO; GO:0003860; F:3-hydroxyisobutyryl-CoA hydrolase activity; IEA:InterPro.
DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR CDD; cd06558; crotonase-like; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR045004; ECH_dom.
DR InterPro; IPR032259; HIBYL-CoA-H.
DR PANTHER; PTHR43176:SF3; 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43176; 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED; 1.
DR Pfam; PF16113; ECH_2; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Isomerase {ECO:0000313|EMBL:PCG15340.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000218323}.
FT DOMAIN 13..335
FT /note="Enoyl-CoA hydratase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF16113"
SQ SEQUENCE 347 AA; 37203 MW; 729B688071AD4871 CRC64;
MTDELIVAVE GAVGRIRLNR PKALHALTTA MCAGVLDALE AWRGDAAVRC VVIDHAEGRG
FCAGGDIRML ADSGAGDGAE ARAFFHTEYR MNHRLFTYAK DTVAFMDGIT MGGGVGISQP
CRYRVATEQT KLAMPETGIG LFPDVGGGWY LSRLPGRIGQ YLALTGHRLD GAECLALGLA
THFVPADRVE EAKAAIAARP DDVAAALDGL SADPGAAAIL AQRADIDRLF ASDRLEEVFA
ALAADDGDFA RATLATLKAK SPQTMKVSLK LLLDGRTMPT FEDEMRQEYA VGSRVVQRHD
FLEGVRAVIV DKDNAPRWDP ATPEGVSDHV IDQIFAPLPD DEAWTPN
//
