ID A0A2A4IZI4_HELVI Unreviewed; 586 AA.
AC A0A2A4IZI4;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE RecName: Full=Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein {ECO:0000259|PROSITE:PS00624};
GN ORFNames=B5V51_9579 {ECO:0000313|EMBL:PCG65171.1};
OS Heliothis virescens (Tobacco budworm moth).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Noctuoidea;
OC Noctuidae; Heliothinae; Heliothis.
OX NCBI_TaxID=7102 {ECO:0000313|EMBL:PCG65171.1, ECO:0000313|Proteomes:UP000218220};
RN [1] {ECO:0000313|EMBL:PCG65171.1, ECO:0000313|Proteomes:UP000218220}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HvINT- {ECO:0000313|EMBL:PCG65171.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:PCG65171.1};
RA Fritz M.L., Deyonke A.M., Papanicolaou A., Micinski S., Westbrook J.,
RA Gould F.;
RT "Contemporary evolution of a Lepidopteran species, Heliothis virescens, in
RT response to modern agricultural practices.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|PIRSR:PIRSR000137-2};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PCG65171.1}.
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DR EMBL; NWSH01004383; PCG65171.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A4IZI4; -.
DR STRING; 7102.A0A2A4IZI4; -.
DR Proteomes; UP000218220; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.30.560.10; Glucose Oxidase, domain 3; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR11552:SF147; CHOLINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11552; GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS00624; GMC_OXRED_2; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|PIRSR:PIRSR000137-2};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Reference proteome {ECO:0000313|Proteomes:UP000218220}.
FT DOMAIN 278..292
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00624"
FT BINDING 242
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
SQ SEQUENCE 586 AA; 64780 MW; 7C309D4CB37958F1 CRC64;
MLTRPSLPEA DVTDGDSFGF IIVGAGSSGS VVANRLSEIE NAKILLIEAG PDAPLEADVP
GTEGALINTI YDWQYLTVNN GKTDQGLING SVGWHRGKMF GGCSSINGMI YVKGNDHDYQ
RWYDAGNTEW SVDEVRRCFK KAESLQNVEL LNNPAARETY GHDGPLFINK FNSTFKPYLE
NVIDSWDEIG FRRVPDLNTE NIMTSGFITA TAANGIRQSI DRAYLLPIAN RKNLYIMKSA
LVTKILIDGN LTAIGVEVEK DGIKKIFYAS KEVILSAGPI SSPQLLMLSG IGPKEHLEAN
NITTIVDSPM VGQNLKDHNF VPVFIYADVP DQPKESDTFL SVLTYLADRQ GSLAFSNLLS
DAIALYSTEK NPKYANCQSH MSIIPKNTTT LKQSFMAAFR YNESVMDSIV ELNENHGIFF
FHFNLLHPIS SGNISLNSNE PKDAPLIYPN YFEDARDLET AAKGVKMLTK ILETKYFKSI
NAFLGRMNLP ACDDFELDGV EYWKCVAVNL VTTIFHPVST CKMGSDISTS VVDSRLRVHG
VKNLRVIDSS VMPDTISGNT NGPSVMIGER ASELVKEDYY NELIGY
//
