ID A0A2A4J1V5_HELVI Unreviewed; 1819 AA.
AC A0A2A4J1V5;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=Cadherin domain-containing protein {ECO:0000259|PROSITE:PS50268};
GN ORFNames=B5V51_9273 {ECO:0000313|EMBL:PCG65392.1};
OS Heliothis virescens (Tobacco budworm moth).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Noctuoidea;
OC Noctuidae; Heliothinae; Heliothis.
OX NCBI_TaxID=7102 {ECO:0000313|EMBL:PCG65392.1, ECO:0000313|Proteomes:UP000218220};
RN [1] {ECO:0000313|EMBL:PCG65392.1, ECO:0000313|Proteomes:UP000218220}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HvINT- {ECO:0000313|EMBL:PCG65392.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:PCG65392.1};
RA Fritz M.L., Deyonke A.M., Papanicolaou A., Micinski S., Westbrook J.,
RA Gould F.;
RT "Contemporary evolution of a Lepidopteran species, Heliothis virescens, in
RT response to modern agricultural practices.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PCG65392.1}.
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DR EMBL; NWSH01004181; PCG65392.1; -; Genomic_DNA.
DR Proteomes; UP000218220; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 10.
DR Gene3D; 2.60.40.60; Cadherins; 11.
DR InterPro; IPR039808; Cadherin.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR020894; Cadherin_CS.
DR PANTHER; PTHR24027; CADHERIN-23; 1.
DR PANTHER; PTHR24027:SF422; NEURAL-CADHERIN 2-RELATED; 1.
DR Pfam; PF00028; Cadherin; 7.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 11.
DR SUPFAM; SSF49313; Cadherin-like; 10.
DR PROSITE; PS00232; CADHERIN_1; 5.
DR PROSITE; PS50268; CADHERIN_2; 11.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; EGF-like domain {ECO:0000256|ARBA:ARBA00022536};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000218220};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..1819
FT /note="Cadherin domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5013217982"
FT TRANSMEM 1366..1391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1567..1593
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 40..141
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 142..262
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 275..384
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 385..497
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 512..599
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 600..699
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 700..800
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 801..901
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 902..1008
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1013..1124
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1135..1262
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT REGION 1615..1634
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1819 AA; 198214 MW; A1527114260F8FF3 CRC64;
MARWSALQHG RPTAWLVFFS LLQVARATPG PCEVETGQSS IIVDIEESRG DQVNQSTVPV
DLPIVGDPDV DVILSTVFPK GPTLFQLDGK RLQLLQPLDR DADNLSHMVF QLVCQVKATK
KRRTIPVIVR VSDINDNAPV FQGTPYEANV SELIPIGTTI FSGIKATDLD AGVNGLAEYF
IIPGDNQTLE AQNAVDGYGS FAIPLPHQGQ VTVNRSLDYE RTQKYLVTIL ASDRARDTKR
RLSSTTTMTV NVLDDDDQDP SFIYKGCTLH EGACFNPEYT SFVDSSVLAG LLTIKPEKIQ
AVDMDTLDAR IKYSIETGEP DSWDKYFAID PNTGAVRQLV PVDTSIAKKF QLVIKAEEVT
EARRFTTAKL TITVRPVDAS PPVIEASANE GMVEENSPKG TKVVDINGQP IRLTVSDPDL
GPGDPVPKYK FELTANFFDI DKDGYLVVND DKLDRDPPNP GKLRFQVVAR EANGVAASDP
YSLAVQLLDQ NDNAPVIPKT QPITVPASLE PTAVHTVEAI DIDEGENARI TYSIYHVSNN
GGNKFTIHPN TGVISSTGRL QAGEQYSVTV RATDAKGLSS QGIVELSVAP GPNTRPPQFS
SRDYYAPVSE GAAINSTVTT VTAKDPENEQ VTYSIASGND LRQFAIGSNT GIITVIRSLD
REVLTRYQLM VRAEDPGRLS STATVNIKVT DINDNNPKFD EDSYLFHVKE GAANEFVGYV
HATDIDDGMN AVVSYSIPTH LPFSIDNGTG MITTNTKLDY ETTKDYAFVV TATDGAIDKR
LGTASVTVQV TDVPDEAPVF AMAVYSVHVP ENAPNYPVVK VEAEDPDTIP EITYTIIMGD
TELFSIDRKS GLIRTLKPLD RETSARHQIV VGTEENNTGG QGSNTTVEVF VDDKNDNAPI
FTSVVRPVTI EDSSSIGSLV QTVVATDSDA TPPNNRVRYK LVGRGKASIY FHVEPDTGAV
RVRDDLRKET DSEYTVDVQA YDQGEPMMSS VSTLTVYVSH SATVPPDVGL GFADTLYTEH
VAENSPNGTL IRILPLLNKR EHSPDTPLKC RLTESSQKGV FYVKLTEERD CAIYLNTSSL
DYETLAEYSL EVQLESIQGL INPESSKATI KVHVTDANDN APMFVFPEQS SIEAAKGKYY
AIVTKDMLLG TNVLQVKAKD RDSGDFGKVE YQKNSWTKAA EEYFSLDTDT GVITNTKTFE
NVPKDVLPFK FSVTARDNPN SAQDYNISRA SVVINLLQKE NQLVVEVADL NADTMRRRSR
SLLTAIEEKT GLYAGLEKLT SRHYLGENGT LESDAKGTDV WLYLLDPATG EILSRESKPV
KKAIESGVHK AVAARLQTAV GAVRAPLQAA EHARRPHVAA APLATALPAA LIALAAVVLV
AAIAATIYIC ASWNRYKKHK EQAIQQYGTL SMSMPTPRPA SGYESSEDEP APRYETQINL
LQKENQLVVE VADLNADTMR RRSRSLLTAI EEKTGLYAGL EKLTSRHYLG ENGTLESDAK
GTDVWLYLLD PATGEILSRE SKPVKKAIES GVHKAVAARL QTAVGAVRAP LQAAEHARRP
HVAAAPLATA LPAALIALAA VVLVAAIAAT IYICASWNRY KKHKEQAIQQ YGTLSMSMPT
PRPASGYESS EDEPAPRYET QVLNMAVDDA DLQLDFSPNN HAFNIHSVQY MSKENGERSP
TLSETATTAR ASSVNENGGT LNNMHNGQLF EPIANNSTLI RNTQTLNRRA PNAHPLNNAI
GTLPRVNNNN VGGGLLATTL GRKINGGNNH KKKATQPIMA YDEIPGLQRA SDNDNVTFGK
RNFTGYNYDQ SPVETTTEL
//
