ID A0A2A4JJZ5_HELVI Unreviewed; 1388 AA.
AC A0A2A4JJZ5;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Protein-tyrosine-phosphatase {ECO:0008006|Google:ProtNLM};
GN ORFNames=B5V51_857 {ECO:0000313|EMBL:PCG72387.1};
OS Heliothis virescens (Tobacco budworm moth).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Noctuoidea;
OC Noctuidae; Heliothinae; Heliothis.
OX NCBI_TaxID=7102 {ECO:0000313|EMBL:PCG72387.1, ECO:0000313|Proteomes:UP000218220};
RN [1] {ECO:0000313|EMBL:PCG72387.1, ECO:0000313|Proteomes:UP000218220}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HvINT- {ECO:0000313|EMBL:PCG72387.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:PCG72387.1};
RA Fritz M.L., Deyonke A.M., Papanicolaou A., Micinski S., Westbrook J.,
RA Gould F.;
RT "Contemporary evolution of a Lepidopteran species, Heliothis virescens, in
RT response to modern agricultural practices.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PCG72387.1}.
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DR EMBL; NWSH01001148; PCG72387.1; -; Genomic_DNA.
DR STRING; 7102.A0A2A4JJZ5; -.
DR Proteomes; UP000218220; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR GO; GO:0048666; P:neuron development; IEA:UniProt.
DR CDD; cd00047; PTPc; 2.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 4.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR000242; PTP_cat.
DR InterPro; IPR016130; Tyr_Pase_AS.
DR InterPro; IPR003595; Tyr_Pase_cat.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR PANTHER; PTHR19134; RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE; 1.
DR PANTHER; PTHR19134:SF495; TYROSINE-PROTEIN PHOSPHATASE 69D; 1.
DR Pfam; PF00102; Y_phosphatase; 4.
DR PRINTS; PR00700; PRTYPHPHTASE.
DR SMART; SM00194; PTPc; 3.
DR SMART; SM00404; PTPc_motif; 3.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 4.
DR PROSITE; PS00383; TYR_PHOSPHATASE_1; 3.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 3.
DR PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 3.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000218220};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 261..283
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 497..516
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 350..481
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50055"
FT DOMAIN 586..1090
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50055"
FT DOMAIN 798..836
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
FT DOMAIN 1006..1081
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
FT DOMAIN 1122..1378
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50055"
FT DOMAIN 1296..1369
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
FT REGION 736..773
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 944..981
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1388 AA; 159023 MW; 153E94B0AD43FE48 CRC64;
MTRTRRRGEE NVTYCRTEFA PPDSPPRPRW RKIMENNTYK FKMYLPRVTE RNGPICCYRV
YMVRLPPGNV DWKRLPSPQD IDVIDFKDSS TKFGAYLADV FSHDRFPRDN ELVLGDDEII
FDKDKDYALR HDRCRRCLKR PKRVYHEPER VPITTTTEVD ELYEGEISTD DPIPDEIEDK
KTKRSYNVED FSKNPTMWDK QSDDSDIRVR DGPLDSSSNY TLFVELITSP NPDDTLFSDY
TSILMPAPSP PVVVPSTALE IALQITCAVA AVILLLMIIF CVLQTRRTRK MPAHAQLELH
NPITAAIRYW DNIRGRQPLV SAVPPDIPPI PKDELASAYA QRQVDSDYGF QKEFEMLPEC
FPDRTTHASE ARENQPKNRY PDIKAYDQTR VKLSQIDSIT GSDYINANYV MGYQITFMQL
KIFEKDFSKN PTMWDKQSDD SDIRVRDGPL DSSSNYTLFV ELITSPNPDD TLFSDYTSIL
MPAPSPPVVV PSTALEIALQ ITCAVAAVIL LLMIIFCVLQ TRRTRKMPAH AQLELHNPIT
AAIRYWDNIR GRQPLVSAVP PDIPPIPKDE LASAYAQRQV DSDYGFQKEF EMLPECFPDR
TTHASEAREN QPKNRYPDIK AYDQTRVKLS QIDSITGSDY INANYVMGYQ ERKQFICAQG
PTDTTVNDFW RMIWEHGLEL IVMLTNLEEY SKVKCSKYWP EERGSRAFGN ITVHHVGEKR
YSDYIVRELK ITKQPTNSDG QPIVENNGIA KRNGDIKEAS ESSAPTSPRE VKDSGESRIV
RQYHFLMWKD FAAPENPHSI LKFIKRVNEA WSSMVGRPVV VHCSAGVGRT GTLVALXKLF
YKCEKIYSFA LIRTTHSQER KQFICAQGPT DTTVNDFWRM IWEHGLELIV MLTNLEEYSK
VKCSKYWPEE RGSRAFGNIT VHHVGEKRYS DYIVRELKIT KQPTNSDGQP IVENNGIAKR
NGDIKEASES SAPTSPREVK DSGESRIVRQ YHFLMWKDFA APENPHSILK FIKRVNEAWS
SMVGRPVVVH CSAGVGRTGT LVALDCLLEQ LRATGHVAVF NTVAELRRQR NFLVQSLKQY
VFVYRALVEY AHYGDTEINA SRLKPAVDKL RNTPDHADKC LMEIEFEKML NSPVAEPLKS
MGAGAGEELR ARNRSPECLP YDRNRVILTP IPGRDFSTYI NASFIEAYDN SEGFIITQDP
LPNTIMDFWR MVSEHNVTTI VMLSELGEGK CPRYWDDGTV QYEHISVQYE ESESCPYYTR
RQFRVTNDKS GDVSCVRQLQ YQGWPTARGH VPEVTRGLAE LADAAAPHQP HQGTMLVHCQ
LGTERSPLFV ALCTLIRALR VERRVDVSAT ARHVRSQRAR TIDTFLQYEF LYRAILNYAE
LHNLLEDS
//
