ID A0A2A4JKU8_HELVI Unreviewed; 2640 AA.
AC A0A2A4JKU8;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 03-MAY-2023, entry version 15.
DE RecName: Full=Calponin-homology (CH) domain-containing protein {ECO:0000259|PROSITE:PS50021};
GN ORFNames=B5V51_1210 {ECO:0000313|EMBL:PCG72063.1};
OS Heliothis virescens (Tobacco budworm moth).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Noctuoidea;
OC Noctuidae; Heliothinae; Heliothis.
OX NCBI_TaxID=7102 {ECO:0000313|EMBL:PCG72063.1, ECO:0000313|Proteomes:UP000218220};
RN [1] {ECO:0000313|EMBL:PCG72063.1, ECO:0000313|Proteomes:UP000218220}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HvINT- {ECO:0000313|EMBL:PCG72063.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:PCG72063.1};
RA Fritz M.L., Deyonke A.M., Papanicolaou A., Micinski S., Westbrook J.,
RA Gould F.;
RT "Contemporary evolution of a Lepidopteran species, Heliothis virescens, in
RT response to modern agricultural practices.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the spectrin family.
CC {ECO:0000256|ARBA:ARBA00006826}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PCG72063.1}.
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DR EMBL; NWSH01001222; PCG72063.1; -; Genomic_DNA.
DR STRING; 7102.A0A2A4JKU8; -.
DR Proteomes; UP000218220; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProt.
DR GO; GO:0008091; C:spectrin; IEA:InterPro.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
DR GO; GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.
DR CDD; cd21246; CH_SPTB-like_rpt1; 1.
DR CDD; cd21248; CH_SPTB_like_rpt2; 1.
DR CDD; cd00176; SPEC; 11.
DR Gene3D; 1.20.58.60; -; 15.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR InterPro; IPR016343; Spectrin_bsu.
DR InterPro; IPR002017; Spectrin_repeat.
DR PANTHER; PTHR11915:SF447; SPECTRIN BETA CHAIN; 1.
DR PANTHER; PTHR11915; SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF00435; Spectrin; 20.
DR PIRSF; PIRSF002297; Spectrin_beta_subunit; 2.
DR SMART; SM00033; CH; 2.
DR SMART; SM00150; SPEC; 20.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF46966; Spectrin repeat; 15.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
PE 3: Inferred from homology;
KW Actin capping {ECO:0000256|ARBA:ARBA00022467};
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000218220};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 38..142
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 157..262
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT COILED 976..1010
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1082..1109
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1159..1209
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1382..1409
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1459..1509
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2234..2293
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 2640 AA; 306431 MW; 2BF1757BE8C5B3E5 CRC64;
MTSTEGYELI KKGVDIEVPG LEVYYDKVVI ELRDERESVQ KKTFQKWVNS HLVRVGCRIG
DLYVDMRDGK QLIKLLEVLS GERLPRPTKG KMRIHCLENV DKALQFLREQ RVHLENMGSH
DIVDGNPRLS LGLIWTIILR FQIQDITIEE TDNKETKSAK DALLLWCQMK TAGYNNVNVR
NFTTSWRDGL AFNAIIHKHR PDLIQFDKLH RSNPMHNLNN AFNVAEEKLG LTKLLDAEDI
AVDHPDEKSI ITYVVTYYHY FSKMKQETVQ GKRIGKVVGI AMENDKMMQE YESLTSDLLQ
WIERTIEALG DRTFANSLEG VRQQLIQFAN YRTVEKPPKF VEKGNLEVLL FTLQSRMRAA
NQKPYTPREG KMIHDINRAW ERLEKSEHER ELALREELIR QEKLEQLAAR FNRKAQMRET
WLSENQRLVS QDNFGFDLAA VEAAAKKHEA IETDIFAYEE RVQAVVAVCS ELQGERYHDM
ERVSARRDNV LRLWAYLLEL LRARRARLEL SLQLQQNFQE MLYILDSMEE IKMRLLTDDY
GKHLMGVEDL LQKHALVEAD INVLGERVKV VVGQSQRFLE QEEGGYRPCD PAITVERIQQ
LENAYAELVH LAVERRKRLE DSRKLWQFYW DMADEENWIK EKEQIVSVDD IGHDLTTVYL
LISKHKALEA DVQAHEPQLM SVAAVGDELI SQGHFGADRI QDRLRDILSQ WNHLLDMVSL
RKNRLDAAVR YHQLFADADD IDNWMLDTLR LVSSEDTGVD EAQVQSLLKK HKDVTDELKN
YANVIQQLKQ QAAELSPSDA SSAEVVSRLG AVDARHGELA ELARLRKQRL LDALSLFKLL
AEADAADQWI AEKDRMLDTM LPPKDIDDVE IMKHRYDGFD KEMNANASRV AVVNQLARQL
IHVEHPQAAR IQERQAKLNS AWSALREKAE SKKDDLKSAQ GVQTFHIECR ETVSWIEDKK
RILQQTDNLE MDLNGVMTLQ RRLSGMERDL AAIQARISSL ESEASAIEGD HPEEAQLIRD
RVTMITENWE QLTQMLKERD AKLEEAGDLH RFLRSVDHFQ AWLTKTQTDV ASEDTPSNLA
EAEKLLSQHQ TIKEEIDNYK DEYAKMMEYG EKITAEPSTQ DDPQYMFLRE RLKALREGWA
ELQQMWENRQ QLLTQSLELQ LLQRDARQAE VLLSHQEHRL AKVEPPANLE HAENMIKEHE
AFLTTMEAND DKINSVVQFA NRLVEERHFD ADKIQRKADN IDARRNANRE KALQQMEKLQ
DQLQLHQFLQ DCDELAEWVQ EKNVTAQDDT YRSAKTIHSK WTRHQAFEAE IAANKERLFA
VQNAAEELMK QKPEFLKERD AKLEEAGDLH RFLRSVDHFQ AWLTKTQTDV ASEDTPSNLA
EAEKLLSQHQ TIKEEIDNYK DEYAKMMEYG EKITAEPSTQ DDPQYMFLRE RLKALREGWA
ELQQMWENRQ QLLTQSLELQ LLQRDARQAE VLLSHQEHRL AKVEPPANLE HAENMIKEHE
AFLTTMEAND DKINSVVQFA NRLVEERHFD ADKIQRKADN IDARRNANRE KALQQMEKLQ
DQLQLHQFLQ DCDELAEWVQ EKNVTAQDDT YRSAKTIHSK WTRHQAFEAE IAANKERLFA
VQNAAEELMK QKPEFVEIIS PKMSELQDQF ENLQTTTKEK GERLFDANRE VLLHQTCDDI
DSWMNELEKQ IENTDTGTDL ASVNILMQKQ QMIETQMAVK AKQVTELETQ AEYLQKTVPD
KMDEIKEKKK SVEQRFEQLK APLLDRQRHL AKKKEAFQFR RDVEDEKLWV HEKMPLATST
DYGNSLFNVQ MLQKKNQSLK TETDNHEPRI LTVISNGQKL IDEGHEDTPE FKQLIDELTA
RWRELKDAID ERKNKLSQWE KAQQYLFDAN EAEAWMSEQE LYMMVEDRGK DEISAQNLMK
KHEILEQAVD DYAHTIRQLG ETVRHLTADE HPLSEQISVK QSQVDKLYAG LKDLAGERRA
KLDEALRLFQ LSREVDDLEQ WITERELVAS SQELGQDYDH VTLLWERFKE FARETQAVGS
ERVATAERIA DQMIAMGHSD NATIAQWKEG LKETWQDLLE LIETRTQMLA ASRELHKYFH
DCKDTLQRVN EKARGVSDEL GRDAISVGAL QRKHHNFMQD LSTLHQQVEA IRSECGRLGA
MYAGEKAAEI TRREDEVRGA WAALAAACQA RTAKLEDADH LYRFLNQVRT LTLWMDDVVR
QMNTGEKPRD VSGVELLMNN HQSLKAEIDT REDNFSACIS LGRELLARQH YASADIKEKL
LQLTNQRNAL LRRWEERWEN LQLILEVYQF ARDAAVAEAW LIAQEPYLMS QELGHTIDEV
ESLIKKHEAF EKSAAAQEDR FSALQRLTTL EQRESSMWPS AQPWDKCDES NFTYQPPPAA
RSHAPLTIQI NKNERPVSQI VEEIITDSNK FNLPDKIKAR VLNINYANNQ RKNDSYLWSV
ANHNSLSTIS EDSVPNSPLM SPTSPEIYSS VFFEFPDQVE KANEYLACID LILWERLSYL
NVYPNVSLLR HKSNSSSKSS LKRFIRKWSK KVKPESDIKG EVAVLSLPGL TSSSKAINDL
GKEVKSIPLS SSLLLLSQTR NLLFPDGAWY YNYLDSVSVV LVLHVLRLSA DGMKRMFLHE
//
