ID A0A2A4K195_HELVI Unreviewed; 917 AA.
AC A0A2A4K195;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 13-SEP-2023, entry version 11.
DE RecName: Full=PXA domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=B5V51_6657 {ECO:0000313|EMBL:PCG77664.1};
OS Heliothis virescens (Tobacco budworm moth).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Noctuoidea;
OC Noctuidae; Heliothinae; Heliothis.
OX NCBI_TaxID=7102 {ECO:0000313|EMBL:PCG77664.1, ECO:0000313|Proteomes:UP000218220};
RN [1] {ECO:0000313|EMBL:PCG77664.1, ECO:0000313|Proteomes:UP000218220}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HvINT- {ECO:0000313|EMBL:PCG77664.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:PCG77664.1};
RA Fritz M.L., Deyonke A.M., Papanicolaou A., Micinski S., Westbrook J.,
RA Gould F.;
RT "Contemporary evolution of a Lepidopteran species, Heliothis virescens, in
RT response to modern agricultural practices.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PCG77664.1}.
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DR EMBL; NWSH01000295; PCG77663.1; -; Genomic_DNA.
DR EMBL; NWSH01000295; PCG77664.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A4K195; -.
DR Proteomes; UP000218220; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR InterPro; IPR003114; Phox_assoc.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR PANTHER; PTHR22775; SORTING NEXIN; 1.
DR PANTHER; PTHR22775:SF44; SORTING NEXIN-14; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF02194; PXA; 1.
DR Pfam; PF00615; RGS; 1.
DR SMART; SM00312; PX; 1.
DR SMART; SM00313; PXA; 1.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR PROSITE; PS51207; PXA; 1.
DR PROSITE; PS50132; RGS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000218220};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 18..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 115..277
FT /note="PXA"
FT /evidence="ECO:0000259|PROSITE:PS51207"
FT DOMAIN 313..442
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
SQ SEQUENCE 917 AA; 103955 MW; 0DCE2E3EBDC2C3C1 CRC64;
MSERCQTKLT EKFDNKNYII YFGILCTAIA VLYFYRFHFG TIAFSYVLGC LACYYGLNSN
ILHDYIDKLK CHFAGETYKD VQEVPVRGCD TCGSKNCNRH DSSVSTEPWV GLQIHKQLDQ
AIEDFYNTIL DQFINSWYGK VTLQPFFVDE LRYQLRYASA CLLQRAVKIN YARFITSRLV
PCALRHYSVC AARGAALDSK LALHPAAANR NAELKYLRCI TNAIMPYLLK NNELNNSVFR
VLIREIFAGW VLLSLTDVLA DPYILNTLIV LATGDETMAQ LPTTPNYKVE FLETFVRQTE
SMYSQRCKLL RVELDAVISD QELLYAFMQY MKTASHLHLL QFYNDIKSFQ TKILNPDLNS
SEEESLHRAA KAMYTTYLRD GVPLPIFGLL AEELEQLLKQ EHSINKFQTS RALYQAARQS
HAVLEKLWLP KFLHSEEFYK LLIGSRIPTG YQKQMVKKPH DKLLNTALKL GHRLKGALRP
QAVDGQVLDC YTNCDESEGD GVDNMDILKY LDNLAIEESL RGQDLSTYKV VLTNVENKLQ
VPPRRGMVRV FTLAVHCAGG PGGAGAALWS VLRSEHDFHL LRSKLHEFHG DRLLLDLPLP
SRRDNSPLET LRYKYEDFIQ RLLQKSLLQT SELLRIFLTE DGDFSMVVQA STLNATSTDL
GNIYQSVAHR LRKEKGQHLE SFLRNLLVSS DIERYQAFSP FLPRKQGTRD VEEAQEMSED
VADAAATRTP RTRNIHATVF QNNFDVEPNV AVVGGEYQDC VVGFSQCAMY LLLKVIRIRS
LFAQVAGTII SLTKQLLDSA FNCVLNRTLE NLLSERRLAH LIRLGHGLLF GRKASTPRTD
PAALRSQARA QLLGTVPPHV ALLASARLPA ALATTFDIIQ TPQLNKQLVY NLLDLCVMEL
FPELGAIDNS PSTLPKS
//
