ID   A0A2A4K248_HELVI        Unreviewed;      1161 AA.
AC   A0A2A4K248;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   RecName: Full=Pre-mRNA-processing factor 6 {ECO:0000256|ARBA:ARBA00020235};
DE   AltName: Full=PRP6 homolog {ECO:0000256|ARBA:ARBA00032140};
DE   AltName: Full=U5 snRNP-associated 102 kDa protein {ECO:0000256|ARBA:ARBA00031070};
GN   ORFNames=B5V51_6498 {ECO:0000313|EMBL:PCG77712.1};
OS   Heliothis virescens (Tobacco budworm moth).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Noctuoidea;
OC   Noctuidae; Heliothinae; Heliothis.
OX   NCBI_TaxID=7102 {ECO:0000313|EMBL:PCG77712.1, ECO:0000313|Proteomes:UP000218220};
RN   [1] {ECO:0000313|EMBL:PCG77712.1, ECO:0000313|Proteomes:UP000218220}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HvINT- {ECO:0000313|EMBL:PCG77712.1};
RC   TISSUE=Whole body {ECO:0000313|EMBL:PCG77712.1};
RA   Fritz M.L., Deyonke A.M., Papanicolaou A., Micinski S., Westbrook J.,
RA   Gould F.;
RT   "Contemporary evolution of a Lepidopteran species, Heliothis virescens, in
RT   response to modern agricultural practices.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PCG77712.1}.
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DR   EMBL; NWSH01000290; PCG77712.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A4K248; -.
DR   STRING; 7102.A0A2A4K248; -.
DR   Proteomes; UP000218220; Unassembled WGS sequence.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 6.
DR   InterPro; IPR003107; HAT.
DR   InterPro; IPR010491; PRP1_N.
DR   InterPro; IPR045075; Syf1-like.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR11246; PRE-MRNA SPLICING FACTOR; 1.
DR   PANTHER; PTHR11246:SF1; PRE-MRNA-PROCESSING FACTOR 6; 1.
DR   Pfam; PF06424; PRP1_N; 1.
DR   Pfam; PF13432; TPR_16; 4.
DR   Pfam; PF14559; TPR_19; 2.
DR   SMART; SM00386; HAT; 20.
DR   SMART; SM00028; TPR; 8.
DR   SUPFAM; SSF81901; HCP-like; 1.
DR   SUPFAM; SSF48452; TPR-like; 5.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000218220};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          21..171
FT                   /note="PRP1 splicing factor N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF06424"
FT   REGION          34..98
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          164..207
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          107..150
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        46..69
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        164..179
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        191..205
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1161 AA;  130865 MW;  26DDDDB7FE4B521F CRC64;
     MSVPPQAFVN KNKKHFLGIP APLGYVAGVG RGATGFTTRS DIGPARDAND VSDDRHAPPA
     AKRKKTEEED DDEDLNDSNY DEFSGYSGSL FSKDPYDKDD AEADAIYESI DKRMDEKRKE
     YREKRLKEDL ERYRQERPKI QQQFSDLKRE LKSVSEDEWS AIPEVGDARN RKQRNPRAEK
     FTPLPDSVLS RNLGGESSSS IDPGSGLASM MPGVMTPGML TPSGDLDLRK IGQARNTLMT
     VKLSQVSDSV TGQTVVDPKG YLTDLQSMIP TYGGDINDIK KARLLLKSVR ETNPNHPPAW
     IASARLEEVT GKVQSARNLI MKGCEVNPSS EELWLEAARL QPRDTARAVI AHAARNLPHS
     VRIWVKAADL EQETKAKRRV YRKALEHIPN SVRLWKAAVE LENPEDARIL LSRAVECCPT
     SVELWLALAR LETYENARKV LNKARENIPT DRQIWVTAAK LEEAHGNTHM VEKIIDRAIT
     SLSANGVEIN REHWFKEAME AEKSGAVHTC QAIIRAVIGH GIEPEDQKHT WMEDAEACAN
     EGAYECARAV YGYALSVFPS KKSIWLRAAY LEKQHGTRAS LEALLQRAVA HCPKSEVLWL
     MGAKSKWLAG DVPAARGILS LAFQANPNSE EIWLAAVKLE SENKEYDRAR RLLSKARASA
     PTPRVMIKSA KLEWALNNLD VALKLLEEAI KVFADYAKLH MMKGQIEEQM EKDEEARNTY
     SQGLKKCATS VPMWILLARL EEKLKNVTKA RSVLEKARLR NPKTAELWLE SVRLERRNGS
     AEIANAVMAK ALQECPSAGR LWAEAIFMES RPQRKTKSRA VAHCPKSEVL WLMGAKSKWL
     AGDVPAARGI LSLAFQANPN SEEIWLAAVK LESENKEYDR ARRLLSKARA SAPTPRVMIK
     SAKLEWALNN LDVALKLLEE AIKVFADYAK LHMMKGQIEE QMEKDEEARN TYSQGLKKCA
     TSVPMWILLA RLEEKLKNVT KARSVLEKAR LRNPKTAELW LESVRLERRN GSAEIANAVM
     AKALQECPSA GRLWAEAIFM ESRPQRKTKS VDALKKCEHD AFVLLAVSQL FWTERKLNKC
     REWFNRTVKI DPDLGDAWAY FYKFELLHGN EQQQEDVKTR CKTAEPHHGE AWCKVSKDIA
     NWCFSTEQIL LLVAKNLPVP T
//