ID A0A2A4K831_HELVI Unreviewed; 884 AA.
AC A0A2A4K831;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=B5V51_13816 {ECO:0000313|EMBL:PCG79812.1};
OS Heliothis virescens (Tobacco budworm moth).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Noctuoidea;
OC Noctuidae; Heliothinae; Heliothis.
OX NCBI_TaxID=7102 {ECO:0000313|EMBL:PCG79812.1, ECO:0000313|Proteomes:UP000218220};
RN [1] {ECO:0000313|EMBL:PCG79812.1, ECO:0000313|Proteomes:UP000218220}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HvINT- {ECO:0000313|EMBL:PCG79812.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:PCG79812.1};
RA Fritz M.L., Deyonke A.M., Papanicolaou A., Micinski S., Westbrook J.,
RA Gould F.;
RT "Contemporary evolution of a Lepidopteran species, Heliothis virescens, in
RT response to modern agricultural practices.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PCG79812.1}.
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DR EMBL; NWSH01000081; PCG79812.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A4K831; -.
DR STRING; 7102.A0A2A4K831; -.
DR Proteomes; UP000218220; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR CDD; cd17974; DEXHc_DHX16; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000218220}.
FT DOMAIN 253..417
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 442..615
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 37..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 884 AA; 102064 MW; EF029B8FEDCAEFB3 CRC64;
MDKMSKRRYS SSSDSAEEDR LKDIRERDEF AKRLKKRDEE KVKKVTESSS KRSYEEAAKR
LKLEAEDREK LLPKLRIHSR RKYLEKRKDD KVIELEADIA DDEYLFDESS LTQRERLERE
HKKTILKLAK EHEKARELEN VQRYHMPQDL GKDAKGEYVE VDEREKLPHS EQQRWEQEQI
KSAFFKFGAK DAKAQDEYEL LLDEQIDFIQ ALQLEGNKEK KEQEEKSQYQ TMRMTIEETK
KSLPVYPFKA SLIEAIKNYQ ILIVEGETGS GKTTQIPQYL HEAGFTEDGK KIGCTQPRRV
AAMSVSARVA QEMNVKLGNE VGYSIRFEDC TSDRTVIKYM TDGTLHREFL SEPDLASYSV
MIIDEAHERT LHTDILFGLV KDITRFRPDL KLLISSATLD AEKFSTFFDD APIFRIPGRR
FPVDIYYTKA PEADYVDACV VSVLQIHATQ PLGDILVFLT GQEEIETCFE MLQERTKRIG
KKLRELLILP VYANLPSDMQ AKIFEPTPEG ARKVVLATNI AETSLTIDNI IYVIDPGFAK
QNNFNSKTGM ESLMVVPISK ASANQRAGRA GRVAPGKCFR LYTAWAYKYE LEDNTIPEIQ
RINLGNAVLT LKALGINDLI HFDFLDPPPH ETLVLALEQL YALGALNHHG ELTKAGRRMA
EFPTDPMLAK MLLASEKYKC SEEIVTIAAM LSVNSSVFYR PKDKIIHADT ARKNFFHPNG
DHLTLMNVYN QWLGSEYSVQ WCYENFIQYR SMKRARDVRE QLAGLMERVE IDMVSSLSDD
TNIRKAITAG YFYHIAKFSK GGHYKTVKHN QTVMIHPNSA LFEELPRWVI YHELVFTSKE
FMRQVTEIES KWLLEVAPHY YKAKELEDST NKKMPKTIGK SSNN
//
