ID A0A2A4KT15_9ACTN Unreviewed; 452 AA.
AC A0A2A4KT15;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=MBL fold metallo-hydrolase {ECO:0000313|EMBL:PCG87425.1};
GN ORFNames=CIB93_03095 {ECO:0000313|EMBL:PCG87425.1};
OS Streptomyces sp. WZ.A104.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2023771 {ECO:0000313|EMBL:PCG87425.1, ECO:0000313|Proteomes:UP000217525};
RN [1] {ECO:0000313|EMBL:PCG87425.1, ECO:0000313|Proteomes:UP000217525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WZ.A104 {ECO:0000313|EMBL:PCG87425.1,
RC ECO:0000313|Proteomes:UP000217525};
RA Xu L., He S., Yan X.;
RT "Isolation and Genomic Analysis of a Bioactive Actinomycete Associated with
RT Cyanobacterium Lyngbya cf. aestuarii.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000217525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WZ.A104 {ECO:0000313|Proteomes:UP000217525};
RA Jiao Y., Han B.;
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PCG87425.1}.
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DR EMBL; NWVL01000004; PCG87425.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A4KT15; -.
DR OrthoDB; 3196337at2; -.
DR Proteomes; UP000217525; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0050313; F:sulfur dioxygenase activity; IEA:InterPro.
DR GO; GO:0006749; P:glutathione metabolic process; IEA:InterPro.
DR CDD; cd07724; POD-like_MBL-fold; 1.
DR CDD; cd00158; RHOD; 1.
DR Gene3D; 3.40.250.10; Rhodanese-like domain; 2.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR044528; POD-like_MBL-fold.
DR InterPro; IPR001763; Rhodanese-like_dom.
DR InterPro; IPR036873; Rhodanese-like_dom_sf.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR PANTHER; PTHR43084; PERSULFIDE DIOXYGENASE ETHE1; 1.
DR PANTHER; PTHR43084:SF1; PERSULFIDE DIOXYGENASE ETHE1, MITOCHONDRIAL; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR Pfam; PF00581; Rhodanese; 2.
DR SMART; SM00849; Lactamase_B; 1.
DR SMART; SM00450; RHOD; 2.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
DR SUPFAM; SSF52821; Rhodanese/Cell cycle control phosphatase; 2.
DR PROSITE; PS50206; RHODANESE_3; 2.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:PCG87425.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000217525}.
FT DOMAIN 261..352
FT /note="Rhodanese"
FT /evidence="ECO:0000259|PROSITE:PS50206"
FT DOMAIN 365..451
FT /note="Rhodanese"
FT /evidence="ECO:0000259|PROSITE:PS50206"
SQ SEQUENCE 452 AA; 47193 MW; 35C21C81A2BFA5AF CRC64;
MFFVEAIELE GLGNRSYLTG GRRTAVAVDP PRDIDRVLAA AARRGVAITH VVETHIHNDY
VTGGLELARI TGAAYLVPAD AHVSFARTAV SDGDTVIIDA ELTLTAVATP GHTPHHTSYV
LSEAGRPVAA FTGGSLLIGT VGRPDLVEPR LTEQLARSQH ASARRLADAL PDETEVLPTH
GFGSFCSSAQ AGGESTTIGK EKAANPALTI DVDTFVAELL AGLEDVPAYY AHMGPANAAG
PAPVDLTAPA VADPDDIAER LAAGEWVVDL RNRIAFAEGH VAGSFNFEAD GKLATYLAWL
IPWGKPVTLL AESAEQLAAA QRELVRVGID RPASAATGGP ADWLRAGESP ASFPRATFAE
LAGQNRGRIV VLDVRRSSER AEGWIEGSVH IPIHQVHRRI DDVPDGTVWV HCAGGMRAGI
AASLLDAAGR DVVAVDDGFG AAAEAGLTIV TG
//
