ID   A0A2A4Q3E5_9BACT        Unreviewed;       330 AA.
AC   A0A2A4Q3E5;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=Magnesium/cobalt efflux protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=COB80_02455 {ECO:0000313|EMBL:PCH91479.1};
OS   Candidatus Kaiserbacteria bacterium.
OC   Bacteria; Candidatus Kaiserbacteria.
OX   NCBI_TaxID=2030810 {ECO:0000313|EMBL:PCH91479.1, ECO:0000313|Proteomes:UP000218803};
RN   [1] {ECO:0000313|Proteomes:UP000218803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Tully B.J., Wheat C.G., Glazer B.T., Huber J.A.;
RT   "A dynamic microbial community with high functional redundancy inhabits the
RT   cold, oxic subseafloor aquifer.";
RL   Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PCH91479.1}.
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DR   EMBL; NVSE01000021; PCH91479.1; -; Genomic_DNA.
DR   Proteomes; UP000218803; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0010960; P:magnesium ion homeostasis; IEA:InterPro.
DR   CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR   Gene3D; 3.10.580.10; CBS-domain; 1.
DR   InterPro; IPR045095; ACDP.
DR   InterPro; IPR000644; CBS_dom.
DR   InterPro; IPR046342; CBS_dom_sf.
DR   InterPro; IPR002550; CNNM.
DR   InterPro; IPR044751; Ion_transp-like_CBS.
DR   PANTHER; PTHR12064; METAL TRANSPORTER CNNM; 1.
DR   PANTHER; PTHR12064:SF59; UNEXTENDED PROTEIN; 1.
DR   Pfam; PF00571; CBS; 1.
DR   Pfam; PF01595; CNNM; 1.
DR   SUPFAM; SSF54631; CBS-domain pair; 1.
DR   PROSITE; PS51371; CBS; 1.
DR   PROSITE; PS51846; CNNM; 1.
PE   4: Predicted;
KW   CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW   ProRule:PRU01193}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW   ProRule:PRU01193};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|PROSITE-
KW   ProRule:PRU01193}.
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        54..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        80..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        110..128
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          1..172
FT                   /note="CNNM transmembrane"
FT                   /evidence="ECO:0000259|PROSITE:PS51846"
FT   DOMAIN          255..313
FT                   /note="CBS"
FT                   /evidence="ECO:0000259|PROSITE:PS51371"
SQ   SEQUENCE   330 AA;  36586 MW;  4DE43846E059ABAA CRC64;
     MEYILIFILL VFSALFSGLT LGLMSWDAQD LKRKADSGDA DAALLYPVRR DGNLLLTTLL
     IGNVLVNAVL SVFLGSLTTG LIAVAAATVL IVIFGEILPQ AIFNRNAIYL GARFVWIVHV
     FIFLLYPITK PIAWALTKVL GTELPSIYSK QELIKLIEDH EDDHNSEVDE DEERIVTGAL
     TFSDKKVEDI MTPRTVVRAF XVTDTVDDTL LQEVRESGLS RFPVYSDDMD TIVGXLYSSQ
     LIGSENTGKS VGDVASSEVR FIRESTSLDD ALQSFLKTHK HLSIVQDEFG GMAGVLTLED
     VLEEIIRTEI VDESDLHEDM RAFAKETDTQ
//