ID A0A2A4RXD7_9CHLR Unreviewed; 246 AA.
AC A0A2A4RXD7;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Endonuclease {ECO:0000313|EMBL:PCI13511.1};
GN ORFNames=COB68_14060 {ECO:0000313|EMBL:PCI13511.1};
OS SAR202 cluster bacterium.
OC Bacteria; Chloroflexota; SAR202 cluster.
OX NCBI_TaxID=2030829 {ECO:0000313|EMBL:PCI13511.1, ECO:0000313|Proteomes:UP000217661};
RN [1] {ECO:0000313|Proteomes:UP000217661}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Tully B.J., Wheat C.G., Glazer B.T., Huber J.A.;
RT "A dynamic microbial community with high functional redundancy inhabits the
RT cold, oxic subseafloor aquifer.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PCI13511.1}.
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DR EMBL; NVSQ01000078; PCI13511.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A4RXD7; -.
DR Proteomes; UP000217661; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR CDD; cd00056; ENDO3c; 1.
DR Gene3D; 1.10.1670.10; Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal); 1.
DR InterPro; IPR011257; DNA_glycosylase.
DR InterPro; IPR003265; HhH-GPD_domain.
DR InterPro; IPR023170; HhH_base_excis_C.
DR InterPro; IPR000445; HhH_motif.
DR PANTHER; PTHR10359; A/G-SPECIFIC ADENINE GLYCOSYLASE/ENDONUCLEASE III; 1.
DR PANTHER; PTHR10359:SF19; DNA REPAIR GLYCOSYLASE MJ1434-RELATED; 1.
DR Pfam; PF00633; HHH; 1.
DR Pfam; PF00730; HhH-GPD; 1.
DR PIRSF; PIRSF001435; Nth; 1.
DR SMART; SM00478; ENDO3c; 1.
DR SUPFAM; SSF48150; DNA-glycosylase; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Endonuclease {ECO:0000313|EMBL:PCI13511.1};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nuclease {ECO:0000313|EMBL:PCI13511.1}.
FT DOMAIN 58..219
FT /note="HhH-GPD"
FT /evidence="ECO:0000259|SMART:SM00478"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 246 AA; 27029 MW; E6AF18E2EADB0524 CRC64;
MAARRRTKKL KSPAQTSSDP ADLPAILLEV HRRLYQSYGP QGWWPGDGPA DVIIGAILTQ
AAAWTNVEMA IANLKEAGCW SLEAIDSQPE EVLAEIIRPS GYFNAKARKL KAFARHLQLN
HDGDLNKMLS QETAALRDEL LSIHGIGPET ADDIVLYAAG KPSFVIDSYT HRIVQRLGIA
GEEQTKSYDG CQAFFHDNLP ADAPLFNEYH ALLDRHAKEA CAKTPRCHGC CLLDLCDTGK
RALPAD
//
