ID A0A2A4WB08_9GAMM Unreviewed; 407 AA.
AC A0A2A4WB08;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Type II secretion system protein F {ECO:0000313|EMBL:PCI67424.1};
GN ORFNames=COB33_12370 {ECO:0000313|EMBL:PCI67424.1};
OS Thiotrichaceae bacterium.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC Thiotrichaceae.
OX NCBI_TaxID=2030882 {ECO:0000313|EMBL:PCI67424.1, ECO:0000313|Proteomes:UP000217494};
RN [1] {ECO:0000313|Proteomes:UP000217494}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Tully B.J., Wheat C.G., Glazer B.T., Huber J.A.;
RT "A dynamic microbial community with high functional redundancy inhabits the
RT cold, oxic subseafloor aquifer.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429, ECO:0000256|RuleBase:RU003923}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004429,
CC ECO:0000256|RuleBase:RU003923}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the GSP F family.
CC {ECO:0000256|ARBA:ARBA00005745, ECO:0000256|RuleBase:RU003923}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PCI67424.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NVTY01000032; PCI67424.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A4WB08; -.
DR Proteomes; UP000217494; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 1.20.81.30; Type II secretion system (T2SS), domain F; 2.
DR InterPro; IPR003004; GspF/PilC.
DR InterPro; IPR001992; T2SS_GspF/T4SS_PilC_CS.
DR InterPro; IPR018076; T2SS_GspF_dom.
DR InterPro; IPR042094; T2SS_GspF_sf.
DR PANTHER; PTHR30012; GENERAL SECRETION PATHWAY PROTEIN; 1.
DR PANTHER; PTHR30012:SF7; PROTEIN TRANSPORT PROTEIN HOFC HOMOLOG; 1.
DR Pfam; PF00482; T2SSF; 2.
DR PRINTS; PR00812; BCTERIALGSPF.
DR PROSITE; PS00874; T2SP_F; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003923};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003923}.
FT TRANSMEM 173..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 226..241
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 380..400
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 73..196
FT /note="Type II secretion system protein GspF"
FT /evidence="ECO:0000259|Pfam:PF00482"
FT DOMAIN 277..399
FT /note="Type II secretion system protein GspF"
FT /evidence="ECO:0000259|Pfam:PF00482"
SQ SEQUENCE 407 AA; 44123 MW; 81AE071385AE4EB1 CRC64;
MATKTKRKDT FLWEGSDRKG TKVNGEMVGV SPALVKAELR RQGITPKKVK KKPKSLFGGA
GKGKITPQDI ALFSRQMSTM MSSGVPLVQS FDIIGKGHDN PAMATLIMAI KADVEGGNTF
ADALAKHPLQ FDSLYVNLVT AGEHAGILDT LLEKIATYKE KTESMKGKIK KALFYPIAVI
AVAFIITAIL LIFVVPQFED MFNNFGADLP ALTMLVVELS KLAQEWWWAA LMVFAAIFHA
IKQLKQRSTK FNEILDRVVL KAPIIGPIIT KATIARFART LATMFAAGVP LVEAMNTVAG
AAGNSVYTKG ILKMRDEIST GNQLNVTMKQ SGLFPNMVVQ MVAIGEEAGS IDSMLSKVAD
FYEEQVDDAV DGLTSLLEPL IMAFLGVIVG GLVVAMYLPI FKMGEVV
//
