ID   A0A2A4WFC5_9GAMM        Unreviewed;       630 AA.
AC   A0A2A4WFC5;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   SubName: Full=Polysaccharide biosynthesis protein {ECO:0000313|EMBL:PCI68575.1};
GN   ORFNames=COB33_08600 {ECO:0000313|EMBL:PCI68575.1};
OS   Thiotrichaceae bacterium.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC   Thiotrichaceae.
OX   NCBI_TaxID=2030882 {ECO:0000313|EMBL:PCI68575.1, ECO:0000313|Proteomes:UP000217494};
RN   [1] {ECO:0000313|Proteomes:UP000217494}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Tully B.J., Wheat C.G., Glazer B.T., Huber J.A.;
RT   "A dynamic microbial community with high functional redundancy inhabits the
RT   cold, oxic subseafloor aquifer.";
RL   Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC       {ECO:0000256|ARBA:ARBA00007430}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PCI68575.1}.
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DR   EMBL; NVTY01000028; PCI68575.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A4WFC5; -.
DR   Proteomes; UP000217494; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR003869; Polysac_CapD-like.
DR   PANTHER; PTHR43318:SF1; POLYSACCHARIDE BIOSYNTHESIS PROTEIN EPSC-RELATED; 1.
DR   PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR   Pfam; PF13727; CoA_binding_3; 1.
DR   Pfam; PF02719; Polysacc_synt_2; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        21..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        44..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        81..102
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        108..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          288..570
FT                   /note="Polysaccharide biosynthesis protein CapD-like"
FT                   /evidence="ECO:0000259|Pfam:PF02719"
SQ   SEQUENCE   630 AA;  70162 MW;  F8CE4B078DE0C5C3 CRC64;
     MRKKIKLKLQ SRRLAVICHD LLMVVAAWGL AFFTRYNFSL PDSAWAMVWQ TLVVVTIAQA
     IVFWVTGLYK GLWRFASLPD MWNISRAAII GVLAISLCLF LFNRMEGIPR TILLFYPVFL
     VFLLGVPRIA YRMWKEHGFN LKNAAGRKHV LIVGAGRSGE MLVRDLLRER EYLVVGFLDD
     NHRLKGAKVR GIPVLGSIHD IPDVVDVYQV NIIMIAIPSA SSKQMRRIVE QCEQTEVPFR
     TLPGMQDLVS GQSTLNELRE VAIDDLLGRD PVQLDWAGIN QGISGKTILI SGGGGSIGSE
     LCRQIAKLGP AKLILFEKSE FNLYSIGCEL KNDYPNLIFH SVLGDVCDAA SVAHVLKSHA
     PEIIFHAAAY KHVPMLEYQV REAVRNNVLG TRLMAQTAAK FACETFVMIS TDKAVNPANV
     MGASKRASEI FCQALNSRVD THYITVRFGN VLGSAGSVVP LFKEQIARGG PVTVTHPDIT
     RFFMTIPEAS QLILQAACMG KGGEIFVLDM GEPLKISYLA EQMIRLSGKI PGDDIEIKYT
     GLRPGEKLFE ELFYQQEDLL KTGHKKILLA RSTQSEWDEI ESNMAILQKA SDDFDEGLIQ
     ETLHQLVPEL SEQQAISLSN DSNVVEFNRA
//