ID   A0A2A4Z5Z5_9PROT        Unreviewed;       491 AA.
AC   A0A2A4Z5Z5;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=HTH gntR-type domain-containing protein {ECO:0000259|PROSITE:PS50949};
GN   ORFNames=COB13_04310 {ECO:0000313|EMBL:PCJ02423.1};
OS   OCS116 cluster bacterium.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; OCS116 cluster.
OX   NCBI_TaxID=2030921 {ECO:0000313|EMBL:PCJ02423.1, ECO:0000313|Proteomes:UP000218076};
RN   [1] {ECO:0000313|Proteomes:UP000218076}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Tully B.J., Wheat C.G., Glazer B.T., Huber J.A.;
RT   "A dynamic microbial community with high functional redundancy inhabits the
RT   cold, oxic subseafloor aquifer.";
RL   Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC       pyridoxal-phosphate-dependent aminotransferase family.
CC       {ECO:0000256|ARBA:ARBA00005384}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PCJ02423.1}.
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DR   EMBL; NVUS01000004; PCJ02423.1; -; Genomic_DNA.
DR   Proteomes; UP000218076; Unassembled WGS sequence.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   CDD; cd00609; AAT_like; 1.
DR   CDD; cd07377; WHTH_GntR; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR004839; Aminotransferase_I/II.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR   PANTHER; PTHR46577:SF1; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR   Pfam; PF00155; Aminotran_1_2; 1.
DR   Pfam; PF00392; GntR; 1.
DR   SMART; SM00345; HTH_GNTR; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50949; HTH_GNTR; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          14..82
FT                   /note="HTH gntR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50949"
SQ   SEQUENCE   491 AA;  55782 MW;  78DFB8C7EF12C1AC CRC64;
     MDILFSALDK QSAISLRDQL CEKISYQISA GLLKPNQRLP SCRKIARQLD ISRNTVVSAY
     QALIYDGIVE SRERSGYFVH AEARAHCATK DLNQELTKPR KKLFDFMPLD KSFIGYKTII
     RPDNWANYAY PFVCNQMDAK RFPLANWRKC SADILSQSKA VQVMSDYSYD DCDELLTEIQ
     TRILPSRGIV ASKDEILLTS GAQQSIYLTS MIFSNSDRAI AVEDPCYPDA RNIFDVFFNK
     INPIKLDDEG ITCTPELAQS DLVYVTPNHQ YPTSIRMSKQ RRQDLLAFAK RNKIVIIEDD
     YDAKTDFDPQ ILTALKADDT ENNIIYIGSL SKDLNPGLRI GYMVASXDFI LEAKKRRGMM
     IRHLPPFLQL TTAHFIRLGH HDSHISMLQN IYKRRWXXAX XALKKYFPDS QIXSGSGGTN
     FLIDTHQQID FSILEEKALA RGVVIDTLNL CYSDPKQCYG LFRLGVSAIG VNKIAAGIKV
     LREVYEEVXP S
//