ID A0A2A5B6R5_9RICK Unreviewed; 335 AA.
AC A0A2A5B6R5;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Uracil-DNA glycosylase-like domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=COA94_04835 {ECO:0000313|EMBL:PCJ26726.1};
OS Rickettsiales bacterium.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rickettsiales.
OX NCBI_TaxID=2026788 {ECO:0000313|EMBL:PCJ26726.1, ECO:0000313|Proteomes:UP000218523};
RN [1] {ECO:0000313|Proteomes:UP000218523}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Tully B.J., Wheat C.G., Glazer B.T., Huber J.A.;
RT "A dynamic microbial community with high functional redundancy inhabits the
RT cold, oxic subseafloor aquifer.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PCJ26726.1}.
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DR EMBL; NVVL01000049; PCJ26726.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A5B6R5; -.
DR Proteomes; UP000218523; Unassembled WGS sequence.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:UniProt.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR Gene3D; 3.40.470.10; Uracil-DNA glycosylase-like domain; 1.
DR InterPro; IPR002562; 3'-5'_exonuclease_dom.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR005122; Uracil-DNA_glycosylase-like.
DR InterPro; IPR036895; Uracil-DNA_glycosylase-like_sf.
DR PANTHER; PTHR33693; TYPE-5 URACIL-DNA GLYCOSYLASE; 1.
DR PANTHER; PTHR33693:SF3; TYPE-5 URACIL-DNA GLYCOSYLASE; 1.
DR Pfam; PF01612; DNA_pol_A_exo1; 1.
DR Pfam; PF03167; UDG; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR SUPFAM; SSF52141; Uracil-DNA glycosylase-like; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022839};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nuclease {ECO:0000256|ARBA:ARBA00022839}.
FT DOMAIN 13..151
FT /note="Uracil-DNA glycosylase-like"
FT /evidence="ECO:0000259|Pfam:PF03167"
FT DOMAIN 188..331
FT /note="3'-5' exonuclease"
FT /evidence="ECO:0000259|Pfam:PF01612"
SQ SEQUENCE 335 AA; 38508 MW; CD73712A45F4FADB CRC64;
MPFIPVQQER SYFGDGEKSS KICIVGESMS KWEIRSGRVF SGPVGTIYEQ CLHGANLTRA
DVYATNIVKI EAKFTLYYRE KKGFTDLGKE AVNALKKEIS ELDCNIVIAM GEAATFALTG
RMDVTKCRGY IFPCVFNPLL KVIPTIHPAK VQFGDYIARH YISHDMNKAK EHSSYKGLKY
DLTKVEIART YLDAVTWLEE IATWKHVSID IEVINYECSC IGFGKSIDTS IVIPFYGKDL
YTLEQEINLW RLVAIIMYDE NIAKTGQNFI FDMQFLLARN RIVTRGTIYD TMIRHSIAYP
EFLKSLAFLT SIYCNRPYWK DMVSWKKKDQ IKNDA
//
