ID A0A2A5YJD8_9PROT Unreviewed; 1012 AA.
AC A0A2A5YJD8;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Sarcosine oxidase subunit alpha {ECO:0000313|EMBL:PDH64639.1};
GN ORFNames=CNE92_01750 {ECO:0000313|EMBL:PDH64639.1};
OS SAR116 cluster bacterium MED-G05.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; SAR116 cluster.
OX NCBI_TaxID=1986234 {ECO:0000313|EMBL:PDH64639.1, ECO:0000313|Proteomes:UP000219577};
RN [1] {ECO:0000313|EMBL:PDH64639.1, ECO:0000313|Proteomes:UP000219577}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MED-G05 {ECO:0000313|EMBL:PDH64639.1};
RA Haro-Moreno J.M., Lopez-Perez M., De La Torre J., Picazo A., Camacho A.,
RA Rodriguez-Valera F.;
RT "Fine stratification of microbial communities through a metagenomic profile
RT of the photic zone.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PDH64639.1}.
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DR EMBL; NTKW01000004; PDH64639.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A5YJD8; -.
DR Proteomes; UP000219577; Unassembled WGS sequence.
DR GO; GO:0008115; F:sarcosine oxidase activity; IEA:InterPro.
DR GO; GO:0046653; P:tetrahydrofolate metabolic process; IEA:InterPro.
DR Gene3D; 3.10.20.440; 2Fe-2S iron-sulphur cluster binding domain, sarcosine oxidase, alpha subunit, N-terminal domain; 1.
DR Gene3D; 1.10.10.1100; BFD-like [2Fe-2S]-binding domain; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR042204; 2Fe-2S-bd_N.
DR InterPro; IPR041854; BFD-like_2Fe2S-bd_dom_sf.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR028896; GCST/YgfZ/DmdA.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR006277; Sarcosine_oxidase_asu.
DR InterPro; IPR041117; SoxA_A3.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR NCBIfam; TIGR01372; soxA; 1.
DR PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR Pfam; PF13510; Fer2_4; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR Pfam; PF17806; SO_alpha_A3; 1.
DR PIRSF; PIRSF037980; SoxA; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00411; PNDRDTASEI.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 179..444
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
FT DOMAIN 530..612
FT /note="SoxA A3"
FT /evidence="ECO:0000259|Pfam:PF17806"
FT DOMAIN 628..892
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 918..1004
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 1012 AA; 109937 MW; D6D5DC5016F88F8B CRC64;
MGFFSKTPAP QIARLATGGR VNRTKPMTFT FDGKTCQGFA GDTLASALLA NNIHLVGRSF
KYHRPRGIMA AGAEEPNALV RVGRGNLAEP NLRASQVELY DGLYAESQNR FPSLKADVGA
VNSLMSRFFP AGFYYKTFMW PASMWMTYEH VIRRAAGLGR VADDHDDPDR YEKTNAHCDI
LIAGGGAAGL MAALAAARSG ARVILADEQN EFGGWMLAEG DVTIEGGSPA DWVAGIIAEL
AAMPDVTLLP RTTVFGYMDH NYLTLTERVT DHLAVRPSHL PRQRMWKVRA RQVVLAQGAH
ERPLVFSGND LPGVMLSGAV RTFINRYGVV PGNRCVVFTN NDDGYRTALS LQQGGAEAVI
VDLRHEVRSA LIKMAKEAGI RIMTGHAVTI ASGTQRIARV EISPVNEDAT RVLDDPVHMD
CDLLAMSGGL SPAVHLHSQA RGKLAWDEEL LCFKPKSVHE ACFNAGACNG VFGLAKAMAD
GLKAGAAAVR ACGLDAGDHL PPVVTAPPQN WRPMPAWKIP NGQPEGEGPK AFVDFQNDVT
ASDVKLAVRE GYQSVEHVKR YTTLGMATDQ GKTSNINGLA ILADALGDEI PNVGTTTFRM
PYTPANFGAI AGRDIGNLFD PTRLTRMDDW HRAHGATFEH VGQWMRAWYY PQTGESMQEA
VNREVLAART AAGLLDASTL GKIDIQGPDA AEFLNRIYTN GWLKLGIGKC RYGLMLKDDG
MVMDDGVTTR LGENHFHMTT TTGGAAGVLD WLEEWQQTEW PDLKVYLTSV TEEWSVATLS
GPNASKILKA AGIDISLDPA DFPFMSMQDA HIAGLPVRIF RISFTGELSF EINIRARHGL
ALWQLLMNAG RDHGITPYGT EAMHVLRAEK GFIIVGQETD GSVTPHDLGM DWIVSKTKPD
FIGKRALARA SMSDDNRKQL VGLVTRDRKR VIPEGAHAVL EPNQPMPMEM LGQVTSSYYS
PNVGGSIAMA MLKGGRSLKG GTVYLPMLDG DMIEADVVDP IFFDPNGDRI NG
//
