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Database: UniProt
Entry: A0A2A6AUC6_9ALTE
LinkDB: A0A2A6AUC6_9ALTE
Original site: A0A2A6AUC6_9ALTE 
ID   A0A2A6AUC6_9ALTE        Unreviewed;       363 AA.
AC   A0A2A6AUC6;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   08-MAY-2019, entry version 6.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   ORFNames=CA267_14520 {ECO:0000313|EMBL:PDM57093.1};
OS   Alteromonas pelagimontana.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Alteromonadaceae; Alteromonas.
OX   NCBI_TaxID=1858656 {ECO:0000313|EMBL:PDM57093.1, ECO:0000313|Proteomes:UP000219285};
RN   [1] {ECO:0000313|EMBL:PDM57093.1, ECO:0000313|Proteomes:UP000219285}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=5.12 {ECO:0000313|EMBL:PDM57093.1,
RC   ECO:0000313|Proteomes:UP000219285};
RA   Sinha R.K., Krishnan K.P.;
RT   "Draft genome sequence of Alteromonas sp. strain 5.12.";
RL   Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:PDM57093.1}.
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DR   EMBL; NGFM01000018; PDM57093.1; -; Genomic_DNA.
DR   RefSeq; WP_075608842.1; NZ_NGFM01000018.1.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000219285; Unassembled WGS sequence.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000219285};
KW   Reference proteome {ECO:0000313|Proteomes:UP000219285};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156}.
FT   DOMAIN       41    340       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   363 AA;  39540 MW;  1E524F8A33CDA627 CRC64;
     MIKDTVNNVH VSAEDVLVTP DALAAELPVS DSALQAISEA RKTISDIIHG RDHRFLVVCG
     PCSIHDIDAA KDYALRLKEL HESCKDTLFI VMRVYFEKPR TTTGWKGLIN DPHIDGTFDI
     EAGLRKAREL LIWLAELQLP VATEALDPIS PQYLAELFSW SAIGARTAES QTHREMASGL
     SMPVGFKNGT DGSLDIAINA LKSAASGHRF MGINKQGQVS IIGTRGNPDG HIILRGGKQP
     NYDSVCVSEC EGELVNANLT AGLMVDCSHA NSSKDYRRQP LVAQNVVNQI LEGNQSIIGV
     MLESHIHAGS QKAEGKKPDE LEYGVSITDG CIDWATTENL ISQTRDKLIT VLPLRQNKRD
     AVA
//
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