ID A0A2A7MCK4_9CLOT Unreviewed; 400 AA.
AC A0A2A7MCK4;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Cobalt-zinc-cadmium resistance protein CzcB {ECO:0000313|EMBL:VCT82741.1};
DE SubName: Full=Efflux RND transporter periplasmic adaptor subunit {ECO:0000313|EMBL:PEG29582.1};
DE SubName: Full=Membrane fusion component {ECO:0000313|EMBL:CAG9703472.1};
GN Name=yknX {ECO:0000313|EMBL:CAG9703472.1};
GN Synonyms=czcB_1 {ECO:0000313|EMBL:VCT82741.1};
GN ORFNames=CNEO_40645 {ECO:0000313|EMBL:CAG9703472.1},
GN CNEONATNEC25_00301 {ECO:0000313|EMBL:VCT82741.1}, CQ394_16725
GN {ECO:0000313|EMBL:PEG29582.1};
OS Clostridium neonatale.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=137838 {ECO:0000313|EMBL:PEG29582.1, ECO:0000313|Proteomes:UP000220840};
RN [1] {ECO:0000313|EMBL:PEG29582.1, ECO:0000313|Proteomes:UP000220840}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LCDC99A005 {ECO:0000313|EMBL:PEG29582.1,
RC ECO:0000313|Proteomes:UP000220840};
RA Bernard K., Burdz T., Wiebe D., Balcewich B., Alfa M., Bernier A.-M.;
RT "Effective Description of Clostridium neonatale sp. nov. linked to
RT necrotizing enterocolitis in neonates and a clarification of species
RT assignable to the genus Clostridium (Prazmowski 1880) emend. Lawson and
RT Rainey 2016.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:VCT82741.1, ECO:0000313|Proteomes:UP000431451}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NEC25 {ECO:0000313|EMBL:VCT82741.1,
RC ECO:0000313|Proteomes:UP000431451};
RG IHU Genomes;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:CAG9703472.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CC3_PB {ECO:0000313|EMBL:CAG9703472.1};
RA Mesa V.;
RL Submitted (OCT-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; CAKJVE010000004; CAG9703472.1; -; Genomic_DNA.
DR EMBL; PDCJ01000003; PEG29582.1; -; Genomic_DNA.
DR EMBL; UWJD01000001; VCT82741.1; -; Genomic_DNA.
DR RefSeq; WP_058293482.1; NZ_UWJD01000001.1.
DR STRING; 137838.GCA_001458595_00525; -.
DR GeneID; 68875612; -.
DR OrthoDB; 2541666at2; -.
DR Proteomes; UP000220840; Unassembled WGS sequence.
DR Proteomes; UP000431451; Unassembled WGS sequence.
DR Proteomes; UP000789738; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 2.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000220840};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..400
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5041060717"
FT DOMAIN 59..314
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT COILED 121..148
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 400 AA; 43074 MW; 967B12588FB26AEF CRC64;
MKKHLALVLV MLTALSLVGC GSKEIEIKEE SIAVSVQAVK KGEIKNTNSF SGTTKLKDET
DVSVEIGGTV ESIKVEVGQE IHKGDVLLTI KGNDVQDGVN TARAAVESAK ATSDSNIEQT
KISLETALKN AQLAYDEAKR NYEIQTQLYN SDAISEDTYK QVEQGYNQAK QALDSAIKSY
DELLPKVEEA GQKGVGQAKA SYDSVARNLE KLTLTSPVDG IVTAKNCTEN ELIAQGSPAF
TISNPSIIQI DLKITSNDID KFVVGDKVKV TVNGEDAEGT IKTVPSVVNN STSLYTVEVI
ADNSEGKIKG GMAADVEVTT ENKNDTISVL KKAVFEEDNK KYVYVVTADN KAKKVEVQTG
IETAERIEIK SGVNNKDTIV ISGLSRIKDG SKLFTVVKED
//
