ID A0A2A7MNE7_9CLOT Unreviewed; 577 AA.
AC A0A2A7MNE7;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=GGDEF domain-containing protein {ECO:0000313|EMBL:PEG32648.1};
GN ORFNames=CQ394_13430 {ECO:0000313|EMBL:PEG32648.1};
OS Clostridium neonatale.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=137838 {ECO:0000313|EMBL:PEG32648.1, ECO:0000313|Proteomes:UP000220840};
RN [1] {ECO:0000313|EMBL:PEG32648.1, ECO:0000313|Proteomes:UP000220840}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LCDC99A005 {ECO:0000313|EMBL:PEG32648.1,
RC ECO:0000313|Proteomes:UP000220840};
RA Bernard K., Burdz T., Wiebe D., Balcewich B., Alfa M., Bernier A.-M.;
RT "Effective Description of Clostridium neonatale sp. nov. linked to
RT necrotizing enterocolitis in neonates and a clarification of species
RT assignable to the genus Clostridium (Prazmowski 1880) emend. Lawson and
RT Rainey 2016.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PEG32648.1}.
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DR EMBL; PDCJ01000001; PEG32648.1; -; Genomic_DNA.
DR RefSeq; WP_058296790.1; NZ_PDCJ01000001.1.
DR AlphaFoldDB; A0A2A7MNE7; -.
DR STRING; 137838.GCA_001458595_04179; -.
DR OrthoDB; 9804747at2; -.
DR Proteomes; UP000220840; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00077; HDc; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR037522; HD_GYP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43155:SF2; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108; 1.
DR PANTHER; PTHR43155; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108-RELATED; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF13487; HD_5; 1.
DR Pfam; PF08448; PAS_4; 2.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00471; HDc; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS51832; HD_GYP; 1.
DR PROSITE; PS50113; PAC; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Reference proteome {ECO:0000313|Proteomes:UP000220840}.
FT DOMAIN 189..241
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 270..399
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 391..577
FT /note="HD-GYP"
FT /evidence="ECO:0000259|PROSITE:PS51832"
SQ SEQUENCE 577 AA; 65721 MW; DAA41EFE9B982749 CRC64;
MDIKIFRLLV DAVPQPIWIK DKDLRFIYTN KRYIDINNIK KGNIIGLCEE DLYRKEIADK
SNEMCSKALN SMSTVKEKRY TNEGIKVDST VFPLTDDNGE LEGIAGIDIP IISKEESITE
MILDSLQAGI FYKDRELGYL YTNKKFDDLL SKDKESIIEN KNSLNESICE SKNKFIQEDK
KVFETKKTVK KEEKIELGNG ENLYTEIIKT PVLNDNNEVS GIIGLLLDIT DRKKIEKKLK
YLSYTDILTK VYNRTCFEEK AKKIFKEENL PMGIIMGDTN GLKIVNDTLG HEEGDELLKL
TTKVLKDVCK GNELIFRIGG DEFAIIIPKA KENECETLIK NIIDSCNNYK HDLIKISIAL
GYSVTYDLDK SIYDTLKEAE DMVYRKKLLE KNSFNSSVIS SLQATLQEKS LETKAHTERV
VENSIKIGER LSLPLSVMDE LILVAKLHDI GKIGINESIL LKSDNLTEEE FGIIKSHTEK
GYRIIKAANH LESVAKGVLT HHERWDGNGY PLKLKEDKIP LIARIVSVAD AYDVMTTNRV
YKNALSKDEA IRELKKNSGK QFDPNIVKVF IECLESA
//
