ID A0A2A7MVH7_MYCAG Unreviewed; 334 AA.
AC A0A2A7MVH7;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=DNA-binding protein {ECO:0000313|EMBL:GFG51002.1};
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:PEG35321.1};
GN ORFNames=CQY20_22400 {ECO:0000313|EMBL:PEG35321.1}, MAGR_24430
GN {ECO:0000313|EMBL:GFG51002.1};
OS Mycolicibacterium agri (Mycobacterium agri).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=36811 {ECO:0000313|EMBL:PEG35321.1, ECO:0000313|Proteomes:UP000220914};
RN [1] {ECO:0000313|EMBL:PEG35321.1, ECO:0000313|Proteomes:UP000220914}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCUG37673 {ECO:0000313|EMBL:PEG35321.1,
RC ECO:0000313|Proteomes:UP000220914};
RA Tortoli E., Trovato A., Cirillo D.M.;
RT "The new phylogeny of genus Mycobacterium.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:GFG51002.1, ECO:0000313|Proteomes:UP000465302}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 6377 {ECO:0000313|EMBL:GFG51002.1,
RC ECO:0000313|Proteomes:UP000465302};
RX PubMed=31287781;
RA Matsumoto Y., Kinjo T., Motooka D., Nabeya D., Jung N., Uechi K., Horii T.,
RA Iida T., Fujita J., Nakamura S.;
RT "Comprehensive subspecies identification of 175 nontuberculous mycobacteria
RT species based on 7547 genomic profiles.";
RL Emerg. Microbes Infect. 8:1043-1053(2019).
RN [3] {ECO:0000313|EMBL:GFG51002.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JCM 6377 {ECO:0000313|EMBL:GFG51002.1};
RA Matsumoto Y., Motooka D., Nakamura S.;
RL Submitted (FEB-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PEG35321.1}.
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DR EMBL; BLKS01000001; GFG51002.1; -; Genomic_DNA.
DR EMBL; PDCP01000047; PEG35321.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A7MVH7; -.
DR OrthoDB; 9805774at2; -.
DR Proteomes; UP000220914; Unassembled WGS sequence.
DR Proteomes; UP000465302; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06307; PBP1_sugar_binding; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR025997; SBP_2_dom.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR PANTHER; PTHR30146:SF149; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13407; Peripla_BP_4; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000313|EMBL:GFG51002.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000220914};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 5..46
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 334 AA; 36624 MW; 4CD392A21743D215 CRC64;
MAHRFKVREI AQQSGLSEAT VDRVLNKRPG VRETTRAEVM QAIADLEKQR AQLRLNGRRY
LIDVVMQTPQ RFSDAFRAAV EAELPVFAPA MLRARFHLWE TGSTAQMVDA LGRLRGSHGV
ILKAQDDPAV AEAIDRLVDS GVPVVTYATD VPASARCSYV GIDNHGAGVT AAYLMGQWLG
DAPSDVLITL SRNVFRGEGE REVGFRSALR NSGRQIVEVS DSDGIDATNE RLVLEALEAN
PSVEAVYSVG GGNAATVAAF DRLGRRCRVF IAHDLDADNR RLLRDGRISV VLHNDLRADA
RLAMRLILQE HRALPPEPVR PAPIQVVTPF NLPL
//
