ID A0A2A7N6R9_MYCAG Unreviewed; 1021 AA.
AC A0A2A7N6R9;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Cyclase {ECO:0000313|EMBL:PEG39191.1};
GN ORFNames=CQY20_11490 {ECO:0000313|EMBL:PEG39191.1};
OS Mycolicibacterium agri (Mycobacterium agri).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=36811 {ECO:0000313|EMBL:PEG39191.1, ECO:0000313|Proteomes:UP000220914};
RN [1] {ECO:0000313|EMBL:PEG39191.1, ECO:0000313|Proteomes:UP000220914}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCUG37673 {ECO:0000313|EMBL:PEG39191.1,
RC ECO:0000313|Proteomes:UP000220914};
RA Tortoli E., Trovato A., Cirillo D.M.;
RT "The new phylogeny of genus Mycobacterium.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PEG39191.1}.
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DR EMBL; PDCP01000016; PEG39191.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A7N6R9; -.
DR OrthoDB; 5476461at2; -.
DR Proteomes; UP000220914; Unassembled WGS sequence.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR16305:SF28; ADENYLATE CYCLASE 10; 1.
DR PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00044; CYCc; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000220914}.
FT DOMAIN 41..173
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
FT COILED 979..1006
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1021 AA; 110096 MW; 11003AC6325799CC CRC64;
MTAKLICGSC GAQARPSGKF CSECGAALRQ ATRSAEYKQV TVLFADVVQS MDITATLDLE
RAREIITEVL ERSAAVVRRY GGTVEYTGDG VMGLFGAPIA LEDHAFRACL AALAIQEEIG
RVAVDVARRD HVDLRMRVGL NSGQVIAGSM GSESGSSRYA ATGEHVGMAQ RMESVAPPGA
VMLSESTARL VEHAVSLGDA QWVRIKNSDT PVCAYQLAAI GPRQGIVGRA EAAFVGRRWE
MAALEAMVDR AVGGRGGVVA VVGPAGIGKS RVARETAAVA AKRGVEVFWV FCESHTRDVP
FGVVERLLRA GSGVTDLDGQ AACDQLRAAV PADADPQDLL LLDDLLGIAD PAVALPQIDP
EARRRRLTAL VNTTALSRTE PTLFIIEDAH WIDVVSESML ADFLAVIART PSMVLITARP
EYHGVLLRAH GAQTIALDAL GDSDTAALIA SLLGSDPSVA GLAEVIADNA AGNPFFAEEM
VRELAQRGVL SGDRGRYVCS TDVAEVKVPA TIQASISARI DRLSSTARQT LHAASVIGAR
FSSELLAALG IDAVVDELID AEMIDQVSFT PSAQYALHHP LIRAVAYESQ LKSDRADWHR
RLAASIEERE PESVEENAAL IAEHLQAAGE VHAAYGWHMR AAAWSVNRDV GAARVSWEQA
RRIADALPAD DAAQLSMRIA PRTMLCATDY HGQALQASRR FEELGQLCSL AGDKVSLAIG
MTGLGTELLY TGRSREGAQL ASEQMALLES IGDADLTVGL AFVAFVNWFD AGRFDEILHW
SQVVIDLAAG DESKGANFGF GSPLAFALTW RGTARWWLGR PGWRQDYDDA IVMARNSDPA
TLAVCVTWTY GHAMPYGVLR VDDASVRVSE AALRAAESSH DIALYLAKYT LAYALLNRDS
AADRRRGLEL MTRFRDFTRE RGPFLVPVAE LWIARDRARR GERDAAIAAM REAVEELHHA
GRFFYAIVGT AVFVETLLER DAEGDHAEAQ RQVDRLTNLR AGYESAMLDT ILLRLRALLA
R
//
