ID A0A2A7NDE3_MYCAG Unreviewed; 382 AA.
AC A0A2A7NDE3;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Uroporphyrinogen-III synthase {ECO:0000313|EMBL:PEG41471.1};
GN ORFNames=CQY20_05315 {ECO:0000313|EMBL:PEG41471.1};
OS Mycolicibacterium agri (Mycobacterium agri).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=36811 {ECO:0000313|EMBL:PEG41471.1, ECO:0000313|Proteomes:UP000220914};
RN [1] {ECO:0000313|EMBL:PEG41471.1, ECO:0000313|Proteomes:UP000220914}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCUG37673 {ECO:0000313|EMBL:PEG41471.1,
RC ECO:0000313|Proteomes:UP000220914};
RA Tortoli E., Trovato A., Cirillo D.M.;
RT "The new phylogeny of genus Mycobacterium.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PEG41471.1}.
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DR EMBL; PDCP01000006; PEG41471.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A7NDE3; -.
DR OrthoDB; 213853at2; -.
DR Proteomes; UP000220914; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004852; F:uroporphyrinogen-III synthase activity; IEA:InterPro.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0006780; P:uroporphyrinogen III biosynthetic process; IEA:InterPro.
DR CDD; cd06578; HemD; 1.
DR CDD; cd00383; trans_reg_C; 1.
DR Gene3D; 3.40.50.10090; -; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR036108; 4pyrrol_syn_uPrphyn_synt_sf.
DR InterPro; IPR003754; 4pyrrol_synth_uPrphyn_synth.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR039793; UROS/Hem4.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR40082; BLR5956 PROTEIN; 1.
DR PANTHER; PTHR40082:SF1; BLR5956 PROTEIN; 1.
DR Pfam; PF02602; HEM4; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF69618; HemD-like; 1.
DR PROSITE; PS51755; OMPR_PHOB; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU01091};
KW Reference proteome {ECO:0000313|Proteomes:UP000220914}.
FT DOMAIN 281..374
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT DNA_BIND 281..374
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
SQ SEQUENCE 382 AA; 40992 MW; 2B303833678DF42D CRC64;
MSAPDWAPLT GFRVAVTSAR RADELSALLR KRGAAVTSAA AIEMVPLPDD HELRMHTERL
IDAPPDIVIA TTGIGFRGWV AAADGWGLAN ELIASLRAAR IVSRGPKATG ALRAAGLPEE
WSPESESSRE LLQYLLEGGI AGRRIAVQLH GATDDWDPFP EFLDRLRAAG ADVVPIRVYR
WHPAPRNGDF DQLVADIAEQ KFDAVSFTSA PAVAAVLMRA AEMGIEDRLL SALRTNVHAM
CVGPVTARPL VRLGVPTSAP ERMRLGALAR HITDELPLLQ SRTLQVAGHK LEIRGTCVVV
DGVVKELSPA GMATIRALAH RPGTVVCRAD LLRALPGSGT DTHAVETAVL RLRTALGDKN
IVSTVVKRGY RLPVDEPLAR AQ
//
