ID A0A2A7SPS1_9ENTE Unreviewed; 296 AA.
AC A0A2A7SPS1;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=PTS fructose transporter subunit IIC {ECO:0000313|EMBL:NAA81142.1};
DE SubName: Full=PTS system mannose/fructose/sorbose-specific IIC component {ECO:0000313|EMBL:RCA11248.1};
DE SubName: Full=PTS system, mannose/fructose/sorbose-specific IIC component {ECO:0000313|EMBL:STP39558.1};
DE EC=2.7.1.- {ECO:0000313|EMBL:STP39558.1};
GN Name=agaC_1 {ECO:0000313|EMBL:STP39558.1};
GN Synonyms=agaC_3 {ECO:0000313|EMBL:STP30825.1};
GN ORFNames=EA71_02003 {ECO:0000313|EMBL:RCA11248.1}, GUJ97_11295
GN {ECO:0000313|EMBL:NAA81142.1}, NCTC8129_03080
GN {ECO:0000313|EMBL:STP30825.1}, NCTC8130_02140
GN {ECO:0000313|EMBL:STP39558.1};
OS Enterococcus durans.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=53345 {ECO:0000313|EMBL:STP39558.1, ECO:0000313|Proteomes:UP000254113};
RN [1] {ECO:0000313|EMBL:RCA11248.1, ECO:0000313|Proteomes:UP000252797}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=4EA1 {ECO:0000313|EMBL:RCA11248.1,
RC ECO:0000313|Proteomes:UP000252797};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A.M., Van Tyne D., Lebreton F., Saavedra J.T., Gilmore M.S.,
RA Manson Mcguire A., Clock S., Crupain M., Rangan U., Young S.,
RA Abouelleil A., Cao P., Chapman S.B., Griggs A., Priest M., Shea T.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Enterococcus durans 4EA1.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000254070, ECO:0000313|Proteomes:UP000254113}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC8129 {ECO:0000313|EMBL:STP30825.1,
RC ECO:0000313|Proteomes:UP000254070}, and NCTC8130
RC {ECO:0000313|EMBL:STP39558.1, ECO:0000313|Proteomes:UP000254113};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:NAA81142.1, ECO:0000313|Proteomes:UP000444134}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BIOML-A60 {ECO:0000313|EMBL:NAA81142.1,
RC ECO:0000313|Proteomes:UP000444134};
RX PubMed=31477907; DOI=.1038/s41591-019-0559-3;
RA Poyet M., Groussin M., Gibbons S.M., Avila-Pacheco J., Jiang X.,
RA Kearney S.M., Perrotta A.R., Berdy B., Zhao S., Lieberman T.D.,
RA Swanson P.K., Smith M., Roesemann S., Alexander J.E., Rich S.A., Livny J.,
RA Vlamakis H., Clish C., Bullock K., Deik A., Scott J., Pierce K.A.,
RA Xavier R.J., Alm E.J.;
RT "A library of human gut bacterial isolates paired with longitudinal
RT multiomics data enables mechanistic microbiome research.";
RL Nat. Med. 25:1442-1452(2019).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; WXTH01000042; NAA81142.1; -; Genomic_DNA.
DR EMBL; LEPB01000004; RCA11248.1; -; Genomic_DNA.
DR EMBL; UGIF01000002; STP30825.1; -; Genomic_DNA.
DR EMBL; UGIP01000002; STP39558.1; -; Genomic_DNA.
DR RefSeq; WP_005875514.1; NZ_WXTW01000041.1.
DR STRING; 53345.LIU_10545; -.
DR GeneID; 56741868; -.
DR KEGG; edu:LIU_10545; -.
DR OrthoDB; 1649937at2; -.
DR Proteomes; UP000252797; Unassembled WGS sequence.
DR Proteomes; UP000254070; Unassembled WGS sequence.
DR Proteomes; UP000254113; Unassembled WGS sequence.
DR Proteomes; UP000444134; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:InterPro.
DR InterPro; IPR004700; PTS_IIC_man.
DR PANTHER; PTHR32502; N-ACETYLGALACTOSAMINE PERMEASE II COMPONENT-RELATED; 1.
DR PANTHER; PTHR32502:SF28; PHOSPHOTRANSFERASE SYSTEM SUGAR-SPECIFIC EIIC COMPONENT; 1.
DR Pfam; PF03609; EII-Sor; 1.
DR PROSITE; PS51106; PTS_EIIC_TYPE_4; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000313|EMBL:STP39558.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 23..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 48..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 95..114
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 141..164
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 210..230
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 250..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 274..296
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 296 AA; 31579 MW; 1F17421428B66610 CRC64;
MDIQWWQILL LTLYAGYQIL DELQIYSSMS APVFAGLYAG LVMGDLKAGL IIGGSMQLTV
LGVGTFGGAS KIDANSGTIL ATAFSISLGM NPEQAIAAIA VPVASLMIQL DILARFANTY
FAHRIDQHVE TMNYKAIERN FLMGALPWAL SRMVPVFLAL AFGGGLVQNV VAVLNGDLKW
LGDGLSVAGA VLPAVGFAIL LRYLPVKKHI SYLILGFTIT ALLATVFSNV QLLGTSVASV
VKDFPGTFNS LPMLAVALIG LALATISYKN DQKNDQHPVV SQQSQSDEGE IEDDEI
//
