ID A0A2A7V089_COMTR Unreviewed; 331 AA.
AC A0A2A7V089;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=TlyA family RNA methyltransferase {ECO:0000313|EMBL:PEH90884.1};
GN ORFNames=CRM82_05500 {ECO:0000313|EMBL:PEH90884.1};
OS Comamonas terrigena.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Comamonas.
OX NCBI_TaxID=32013 {ECO:0000313|EMBL:PEH90884.1, ECO:0000313|Proteomes:UP000220246};
RN [1] {ECO:0000313|Proteomes:UP000220246}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FDAARGOS_394 {ECO:0000313|Proteomes:UP000220246};
RA Minogue T., Wolcott M., Wasieloski L., Aguilar W., Moore D., Tallon L.,
RA Sadzewicz L., Ott S., Zhao X., Nagaraj S., Vavikolanu K., Aluvathingal J.,
RA Nadendla S., Sichtig H.;
RT "FDA dAtabase for Regulatory Grade micrObial Sequences (FDA-ARGOS):
RT Supporting development and validation of Infectious Disease Dx tests.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TlyA family.
CC {ECO:0000256|ARBA:ARBA00029460}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PEH90884.1}.
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DR EMBL; PDEA01000001; PEH90884.1; -; Genomic_DNA.
DR RefSeq; WP_066540790.1; NZ_UIGV01000002.1.
DR AlphaFoldDB; A0A2A7V089; -.
DR STRING; 1219032.GCA_001515545_03224; -.
DR GeneID; 80800044; -.
DR OrthoDB; 9784736at2; -.
DR Proteomes; UP000220246; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd00165; S4; 1.
DR Gene3D; 3.10.290.10; RNA-binding S4 domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002877; RNA_MeTrfase_FtsJ_dom.
DR InterPro; IPR036986; S4_RNA-bd_sf.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR047048; TlyA.
DR PANTHER; PTHR32319; BACTERIAL HEMOLYSIN-LIKE PROTEIN; 1.
DR PANTHER; PTHR32319:SF0; BACTERIAL HEMOLYSIN-LIKE PROTEIN; 1.
DR Pfam; PF01728; FtsJ; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS50889; S4; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:PEH90884.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000220246};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00182};
KW Transferase {ECO:0000313|EMBL:PEH90884.1}.
FT DOMAIN 63..328
FT /note="Ribosomal RNA methyltransferase FtsJ"
FT /evidence="ECO:0000259|Pfam:PF01728"
FT REGION 200..223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 331 AA; 35540 MW; 6463883B018FE86D CRC64;
MRADVFLVEA GHAATRSQAQ RLIAAGVQWR TMPLAPWTQV AKNGDDIPAG AQVQLLDASE
AKYISRGGLK LEGALAAAGL QVSGLRCLDV GQSTGGFTDC LLQAGAAQVI GVDVGHDQLH
ERLKSDPRVV GVEGLNARAM TAESLVQGCE DALSEVIEEQ EDNDTQPQAP YAWMRNGGMV
DEDYDDSEDA KEQDIESFKA ERAAKDKARA DGTAPVERRR KPGTEDIDIT PVFDFVTGDV
SFISLTLILP QLVPLMGPGA PLLMLVKPQF ELQPGQIGKG GIVRDPALYA EVEQRIRACC
KEVGLKVVGW YDSAIEGGDG NREFFVHATK A
//
