ID   A0A2A8CYH1_9BACT        Unreviewed;       985 AA.
AC   A0A2A8CYH1;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Peptidase M16 {ECO:0000313|EMBL:PEN13627.1};
GN   ORFNames=CRI94_09985 {ECO:0000313|EMBL:PEN13627.1};
OS   Longibacter salinarum.
OC   Bacteria; Rhodothermota; Rhodothermia; Rhodothermales; Salisaetaceae;
OC   Longibacter.
OX   NCBI_TaxID=1850348 {ECO:0000313|EMBL:PEN13627.1, ECO:0000313|Proteomes:UP000220102};
RN   [1] {ECO:0000313|EMBL:PEN13627.1, ECO:0000313|Proteomes:UP000220102}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KCTC 52045 {ECO:0000313|EMBL:PEN13627.1,
RC   ECO:0000313|Proteomes:UP000220102};
RA   Goh K.M., Shamsir M.S., Lim S.W.;
RT   "Draft genome of Longibacter Salinarum.";
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase M16 family.
CC       {ECO:0000256|ARBA:ARBA00007261, ECO:0000256|RuleBase:RU004447}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PEN13627.1}.
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DR   EMBL; PDEQ01000004; PEN13627.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A8CYH1; -.
DR   OrthoDB; 9811314at2; -.
DR   Proteomes; UP000220102; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 4.
DR   InterPro; IPR011249; Metalloenz_LuxS/M16.
DR   InterPro; IPR011765; Pept_M16_N.
DR   InterPro; IPR001431; Pept_M16_Zn_BS.
DR   InterPro; IPR007863; Peptidase_M16_C.
DR   PANTHER; PTHR43690; NARDILYSIN; 1.
DR   PANTHER; PTHR43690:SF34; ZINC PROTEASE PQQL-LIKE; 1.
DR   Pfam; PF00675; Peptidase_M16; 1.
DR   Pfam; PF05193; Peptidase_M16_C; 2.
DR   SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 4.
DR   PROSITE; PS00143; INSULINASE; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Reference proteome {ECO:0000313|Proteomes:UP000220102};
KW   Signal {ECO:0000256|SAM:SignalP}; Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   SIGNAL          1..49
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           50..985
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5013196489"
FT   DOMAIN          82..225
FT                   /note="Peptidase M16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00675"
FT   DOMAIN          242..419
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
FT   DOMAIN          720..896
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
SQ   SEQUENCE   985 AA;  109843 MW;  F8A51A84193D1F88 CRC64;
     MAAPLDGIHP HASSRPSILY MRSSLRSISR LALGAVLLML LAWSPFAQAQ QADADTSEEA
     LPVDPAVRTG TLDNGMRFYI RQNDEPEDRL QLRLALNAGS ILETDAQRGL AHFLEHMLFN
     GTENFEEQKL IDFLERTGME FGPDVNAYTS FDETVYKLRV PTDSLELVKT SFMVLRDWAS
     RATLSEEEID KERGVVIEEW RQSQETAQGR MQDDIVSTLF AGSRYADRLP IGDTSVVKNA
     PYSEVRDYYE TWYRPDLMAI IAVGDMDPDM LETMIRDRFS DFESPSDPQE RKRYDVPAHE
     DTKYAVVTDP EYPVSSVATI FKTDAQPVRS KADFRRMLKE RLFFSMLNAR LSEKAQSGDA
     PFLGAGGFNF TLARPMKGYG LQAQVPEDSI VAGMEALLTE ATRIRQHGFT DSELIRQKRD
     LLRSYETSYN ERENIPSQSL AQQYVQLFLT GESAPGIETE YELAKEIMPT ITLADVNAVT
     STIVADRNRA VLVQMPEKEG LEPPSEDTLA AVLDRVRTKD VEPYEDEMSD VPLMADIPEP
     AGLKSTETID TLGTTVWTLE NGVTVVHKPT EFKDDEIRFT ATSPGGASTI SDDAYRSMRF
     APNVVRQSGV GPFDNTALKK YLQGKSVSVS PYISSRDEGM NGSASPQDLE TMFQLIHSYA
     TAPRIDANAL QSFKQQLTAR LKNRSATPTA ALQDTLVAKV YDNHPRVSPP EIAEVEALIA
     DSLLGYYRTR FADASDFTFT FAGNVPTDSL AQFARTYLGT LPTIERTDEV RAVTPAPPND
     VVEAEVRAGQ GQRSIVLLTY NGDIEYTREN RHALTTLSDV LSIKLREELR EKRGGTYNVG
     VRDNTTGPPY NRYSFTVSFV CDPDRAADLL AAAKAEIDSV RTGGVTADDI AKVQEQQRRS
     RETAMETNSF WVSALDQAFT TESVEPLDIY RYEELVSSST PETVAQTAQS YLNENRYYQV
     VLYPEDFEAN AETSDGEAST EAGEK
//