ID   A0A2A8S564_9BACI        Unreviewed;       448 AA.
AC   A0A2A8S564;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=IS3 family transposase {ECO:0000313|EMBL:PEY99445.1};
GN   ORFNames=CN326_23310 {ECO:0000313|EMBL:PEY99445.1};
OS   Bacillus sp. AFS018417.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=2033491 {ECO:0000313|EMBL:PEY99445.1, ECO:0000313|Proteomes:UP000220085};
RN   [1] {ECO:0000313|EMBL:PEY99445.1, ECO:0000313|Proteomes:UP000220085}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AFS018417 {ECO:0000313|EMBL:PEY99445.1,
RC   ECO:0000313|Proteomes:UP000220085};
RG   Agbiome Team Llc;
RA   Bleich R.M., Grubbs K.J., Santa Maria K.C., Allen S.E., Farag S.,
RA   Shank E.A., Bowers A.;
RT   "Large-scale bioinformatics analysis of Bacillus genomes uncovers conserved
RT   roles of natural products in bacterial physiology.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PEY99445.1}.
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DR   EMBL; NTTM01000099; PEY99445.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A8S564; -.
DR   OrthoDB; 9781005at2; -.
DR   Proteomes; UP000220085; Unassembled WGS sequence.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR025948; HTH-like_dom.
DR   InterPro; IPR001584; Integrase_cat-core.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR048020; Transpos_IS3.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   NCBIfam; NF033516; transpos_IS3; 1.
DR   PANTHER; PTHR46889; TRANSPOSASE INSF FOR INSERTION SEQUENCE IS3B-RELATED; 1.
DR   PANTHER; PTHR46889:SF1; TRANSPOSASE INSO FOR INSERTION SEQUENCE ELEMENT IS911B-RELATED; 1.
DR   Pfam; PF13276; HTH_21; 1.
DR   Pfam; PF13518; HTH_28; 1.
DR   Pfam; PF00665; rve; 1.
DR   Pfam; PF13333; rve_2; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   SUPFAM; SSF48295; TrpR-like; 1.
DR   PROSITE; PS50994; INTEGRASE; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000220085}.
FT   DOMAIN          283..445
FT                   /note="Integrase catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS50994"
FT   REGION          108..133
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   448 AA;  52815 MW;  34FEE28F2D109989 CRC64;
     MTKYSLETKL AAVHAYLDGV ESFQVTAQKH NVNIVMLKKW VAKFREHGLA GLQKGYTDYS
     IEFKMDVLNY INKTGASILE ATTVFNIPSS NTVWMWKELF DTQGIDALQP KKKGRPSMKK
     KPEKNQPEGS EESLKAEIER LRMENAYLKK LPCLNSRKGK VTEQDKAQII YELRHEFKII
     DLVKVADIPR STYYYWVKRM ERPDKYNEVK GMIQRIFYKH QGRYGYRRIT WALRNQGIVL
     NHKTVRRLMS EMNLKSLVRM KKYRSYRGKV GNIAPNILKR EFKATKPNEK WVTDVTEFHI
     HGEKLYLSPI LDLYNGEIIA YNIEKRPVYP LVSKMLDKAF QQLKDGEFPI LHSDQGWHYQ
     MKQYQHVLKE KGITQSMSRK GNCLDNAVIE NFFGLLKSEL LYLQEFESME HFKLELEKYI
     HYYNHDRIKT KLKGMSPVQY RTHSSLAA
//