ID A0A2A8SA03_9BACI Unreviewed; 288 AA.
AC A0A2A8SA03;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE SubName: Full=5'-3' exonuclease {ECO:0000313|EMBL:PEZ05665.1};
GN ORFNames=CN326_12475 {ECO:0000313|EMBL:PEZ05665.1};
OS Bacillus sp. AFS018417.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=2033491 {ECO:0000313|EMBL:PEZ05665.1, ECO:0000313|Proteomes:UP000220085};
RN [1] {ECO:0000313|EMBL:PEZ05665.1, ECO:0000313|Proteomes:UP000220085}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AFS018417 {ECO:0000313|EMBL:PEZ05665.1,
RC ECO:0000313|Proteomes:UP000220085};
RG Agbiome Team Llc;
RA Bleich R.M., Grubbs K.J., Santa Maria K.C., Allen S.E., Farag S.,
RA Shank E.A., Bowers A.;
RT "Large-scale bioinformatics analysis of Bacillus genomes uncovers conserved
RT roles of natural products in bacterial physiology.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PEZ05665.1}.
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DR EMBL; NTTM01000030; PEZ05665.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A8SA03; -.
DR OrthoDB; 9806424at2; -.
DR Proteomes; UP000220085; Unassembled WGS sequence.
DR GO; GO:0017108; F:5'-flap endonuclease activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0033567; P:DNA replication, Okazaki fragment processing; IEA:InterPro.
DR CDD; cd09898; H3TH_53EXO; 1.
DR CDD; cd09859; PIN_53EXO; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR InterPro; IPR020046; 5-3_exonucl_a-hlix_arch_N.
DR InterPro; IPR002421; 5-3_exonuclease.
DR InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR InterPro; IPR020045; DNA_polI_H3TH.
DR InterPro; IPR038969; FEN.
DR InterPro; IPR008918; HhH2.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR PANTHER; PTHR42646:SF2; DNA-DIRECTED DNA POLYMERASE; 1.
DR PANTHER; PTHR42646; FLAP ENDONUCLEASE XNI; 1.
DR Pfam; PF01367; 5_3_exonuc; 1.
DR Pfam; PF02739; 5_3_exonuc_N; 1.
DR SMART; SM00475; 53EXOc; 1.
DR SMART; SM00279; HhH2; 1.
DR SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Exonuclease {ECO:0000313|EMBL:PEZ05665.1};
KW Hydrolase {ECO:0000313|EMBL:PEZ05665.1};
KW Nuclease {ECO:0000313|EMBL:PEZ05665.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000220085}.
FT DOMAIN 2..263
FT /note="5'-3' exonuclease"
FT /evidence="ECO:0000259|SMART:SM00475"
SQ SEQUENCE 288 AA; 32430 MW; 0031DD8C50F9E668 CRC64;
MKKVLLVDGM ALLFRAFYAT SVYGQFMKRQ DGTPTNGIHG YMKHLLTASG TIEPTHIVTC
WDMGSTTFRT EAFSNYKANR GAPPEELIPQ FDLVQEMTAH LSIPVIGMKG YEADDCIGTL
AKAYQNEAEV FILTGDTDLL QLVDTNITVM LLRKGIGNYE YYTPEKIIEE KGVQPWQIVH
AKAFMGDSSD NYPGVKGIGE KTAYKLIQEH GTVTAVLENI TLLTKTQRTK IENDLDNLHM
SLQLAQIHCE VPISCELEEA LHTIDIEKIR FVCEQMNWGR PEMFVNML
//
