ID   A0A2A9BM20_9BACI        Unreviewed;       437 AA.
AC   A0A2A9BM20;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=AGCS family alanine or glycine:cation symporter {ECO:0000313|EMBL:PFG02916.1};
GN   ORFNames=ATG70_4126 {ECO:0000313|EMBL:PFG02916.1};
OS   Bacillus sp. es.036.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=1761764 {ECO:0000313|EMBL:PFG02916.1, ECO:0000313|Proteomes:UP000222003};
RN   [1] {ECO:0000313|EMBL:PFG02916.1, ECO:0000313|Proteomes:UP000222003}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=es.036 {ECO:0000313|Proteomes:UP000222003};
RA   Fredrickson J.;
RT   "Microbial Interactions in Extremophilic Mat Communities.";
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363064};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363064}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC       (TC 2.A.25) family. {ECO:0000256|ARBA:ARBA00009261,
CC       ECO:0000256|RuleBase:RU363064}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PFG02916.1}.
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DR   EMBL; PDIZ01000003; PFG02916.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A9BM20; -.
DR   Proteomes; UP000222003; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR   InterPro; IPR001463; Na/Ala_symport.
DR   NCBIfam; TIGR00835; agcS; 1.
DR   PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR   PANTHER; PTHR30330:SF14; SODIUM_AMINO ACID (ALANINE) SYMPORTER-RELATED; 1.
DR   Pfam; PF01235; Na_Ala_symp; 1.
DR   PRINTS; PR00175; NAALASMPORT.
DR   PROSITE; PS00873; NA_ALANINE_SYMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU363064};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363064};
KW   Symport {ECO:0000256|RuleBase:RU363064};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363064}.
FT   TRANSMEM        12..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        62..86
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        92..113
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        142..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        173..195
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        207..227
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        295..318
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        343..366
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        382..403
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        409..428
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
SQ   SEQUENCE   437 AA;  46350 MW;  32E3D9207174C4F6 CRC64;
     MQAIEAINEI LWGPIMISLL LGTGLFFTIR LGFIQFTGLK EGFRQTFGPL FSKKKQNGIS
     SYQALSTAIA AQVGTGNLAG VATAIAAGGP GAIFWMWISS FLGMATIFAE AVLAQKFRVK
     ENGVVKGGPA YYIRDGLGSK KLAAFFAIAI ICALGFVGNM VQSNSIAEAF QTAFQIPPLV
     IGFGVAILIS LILFGGINRI ARFAGNVVPI MALLYIIGAL MILVLHFDQV LPALSLIVES
     AFTPESAGGG VLGASIKEAI RYGVARGLFS NEAGMGSTPH AHAVAEVKHP AQQGFVAMVG
     VLIDTVIICT VTALVILVTD GASSNLTGIE LTQASFTSGL GSFGVYFIAF SLLFFSFTTI
     LGWAYFGETN VNYLFGEKSV PYYRAAVLIF IVLGTVLNVP FVWQLADTFN AFMVLPNVIA
     LIALSSVVKK SYKELSR
//