ID   A0A2A9CDC8_9BACI        Unreviewed;       303 AA.
AC   A0A2A9CDC8;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=Cobalt-zinc-cadmium efflux system protein {ECO:0000313|EMBL:PFG12393.1};
GN   ORFNames=ATG70_0574 {ECO:0000313|EMBL:PFG12393.1};
OS   Bacillus sp. es.036.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=1761764 {ECO:0000313|EMBL:PFG12393.1, ECO:0000313|Proteomes:UP000222003};
RN   [1] {ECO:0000313|EMBL:PFG12393.1, ECO:0000313|Proteomes:UP000222003}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=es.036 {ECO:0000313|Proteomes:UP000222003};
RA   Fredrickson J.;
RT   "Microbial Interactions in Extremophilic Mat Communities.";
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PFG12393.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; PDIZ01000001; PFG12393.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A9CDC8; -.
DR   OrthoDB; 9809646at2; -.
DR   Proteomes; UP000222003; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1510.10; Cation efflux protein transmembrane domain; 1.
DR   InterPro; IPR002524; Cation_efflux.
DR   InterPro; IPR036837; Cation_efflux_CTD_sf.
DR   InterPro; IPR027469; Cation_efflux_TMD_sf.
DR   NCBIfam; TIGR01297; CDF; 1.
DR   PANTHER; PTHR11562; CATION EFFLUX PROTEIN/ ZINC TRANSPORTER; 1.
DR   PANTHER; PTHR11562:SF17; LD05335P; 1.
DR   Pfam; PF01545; Cation_efflux; 1.
DR   SUPFAM; SSF160240; Cation efflux protein cytoplasmic domain-like; 1.
DR   SUPFAM; SSF161111; Cation efflux protein transmembrane domain-like; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        20..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        46..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        87..106
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        118..142
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        154..181
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        187..204
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   303 AA;  33241 MW;  4245711B998AFC43 CRC64;
     MGHNHSHDHG HTHSANKKAL FISFLLISSF MILEVIGGFV TNSLALLSDA GHMLSDAVAL
     GMSLLAFKLG EKASDQDKTY GYKRFEILAA FLNGIALIGI SIYILWESIN RFIDPPDVAS
     TGMLIIAAIG FIVNVLVAWI LMKGDTSENL NLRSAFLHVL GDLLGSIGAI IAALLIMFVG
     WNYADPIASS IVAVLVLISG IRVTKDSFHV LMEGTPSNID LEEVKKMLTS LDDVHSIHDV
     HIWNITSDFP AFTCHLVVNK GCDRDQLLQL ANQKLHDQFE LSHTTIQMEC DTSDIKNQEN
     NCN
//