ID A0A2A9EFT2_9MICO Unreviewed; 431 AA.
AC A0A2A9EFT2;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Uroporphyrinogen-III synthase {ECO:0000313|EMBL:PFG37145.1};
GN ORFNames=ATL41_1893 {ECO:0000313|EMBL:PFG37145.1};
OS Flavimobilis soli.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Jonesiaceae;
OC Flavimobilis.
OX NCBI_TaxID=442709 {ECO:0000313|EMBL:PFG37145.1, ECO:0000313|Proteomes:UP000221394};
RN [1] {ECO:0000313|EMBL:PFG37145.1, ECO:0000313|Proteomes:UP000221394}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21574 {ECO:0000313|EMBL:PFG37145.1,
RC ECO:0000313|Proteomes:UP000221394};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PFG37145.1}.
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DR EMBL; PDJH01000001; PFG37145.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A9EFT2; -.
DR OrthoDB; 213853at2; -.
DR Proteomes; UP000221394; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004852; F:uroporphyrinogen-III synthase activity; IEA:InterPro.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0006780; P:uroporphyrinogen III biosynthetic process; IEA:InterPro.
DR CDD; cd06578; HemD; 1.
DR CDD; cd00383; trans_reg_C; 1.
DR Gene3D; 3.40.50.10090; -; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR036108; 4pyrrol_syn_uPrphyn_synt_sf.
DR InterPro; IPR003754; 4pyrrol_synth_uPrphyn_synth.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR039793; UROS/Hem4.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR40082; BLR5956 PROTEIN; 1.
DR PANTHER; PTHR40082:SF1; BLR5956 PROTEIN; 1.
DR Pfam; PF02602; HEM4; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF69618; HemD-like; 1.
DR PROSITE; PS51755; OMPR_PHOB; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU01091};
KW Reference proteome {ECO:0000313|Proteomes:UP000221394}.
FT DOMAIN 330..430
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT DNA_BIND 330..430
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
FT REGION 1..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 431 AA; 44085 MW; 114373D9ACC7A1F5 CRC64;
MTTPSTAPGA APVTGAAESG TAAVPAATGA DAAAPASTSP ATAAPARPAV TGTPTSQPGL
DPVLAGLTVL ITADRRSTEL SAALERRGAT IRHAPAMRII PHEYDTELVA ATRALLADPP
STVIATTGIG FRAWIEAADA AGLADDLHAL LERARLIARG PKARGAIQAA GLTADWVAES
ETSAEILDLL LTEGVAGERV AIQQHGSGAD QLDVELAAAG AEVRNLVVYR WGPPADPQAV
VESVRAAALG EVDAVVFTSA PGAHAWLEVV DREGVGKALA TRFADRSLIA AAVGPVTAAP
LVARGIEPVV PERARLGALV RALVSHYEED RTTQVATVAG CLQVRSRAAL LDGHVLPLSP
ATLEVLRVLA ARAGEVVTRA ELLQVLPGLS EDPHTAEVAV ARLRDAVAQH APDARALVQT
VVKRGYRLAV A
//
