ID A0A2A9EKK2_9MICO Unreviewed; 547 AA.
AC A0A2A9EKK2;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=ATJ97_1631 {ECO:0000313|EMBL:PFG39136.1};
OS Georgenia soli.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Bogoriellaceae;
OC Georgenia.
OX NCBI_TaxID=638953 {ECO:0000313|EMBL:PFG39136.1, ECO:0000313|Proteomes:UP000222106};
RN [1] {ECO:0000313|EMBL:PFG39136.1, ECO:0000313|Proteomes:UP000222106}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21838 {ECO:0000313|EMBL:PFG39136.1,
RC ECO:0000313|Proteomes:UP000222106};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SIMILARITY: Belongs to the helicase family. RAD25/XPB subfamily.
CC {ECO:0000256|ARBA:ARBA00006637}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PFG39136.1}.
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DR EMBL; PDJI01000004; PFG39136.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A9EKK2; -.
DR OrthoDB; 3713880at2; -.
DR Proteomes; UP000222106; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR CDD; cd18029; DEXHc_XPB; 1.
DR CDD; cd18789; SF2_C_XPB; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR032438; ERCC3_RAD25_C.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032830; XPB/Ssl2_N.
DR PANTHER; PTHR11274:SF0; GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB; 1.
DR PANTHER; PTHR11274; RAD25/XP-B DNA REPAIR HELICASE; 1.
DR Pfam; PF16203; ERCC3_RAD25_C; 1.
DR Pfam; PF13625; Helicase_C_3; 1.
DR Pfam; PF04851; ResIII; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000222106}.
FT DOMAIN 190..344
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 399..545
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 547 AA; 61038 MW; 840F0D6B00DC7070 CRC64;
MPDGPLIVQS DKSLLLEVDH PRAREARRAI APFAELERAP EHIHTYRLTP LGLWNARAAG
HDAEQVVNAL IEYSRYAVPH TLLVDVAETM DRYGRLQLVK HPTHGLVLHA LDRPVLEEVL
RSKRIKGLVG ERIDAEDVVV HPSERGRLKQ VLVKLGWPAE DLAGYVDGEA HAIDLAQDGW
HLRPYQEEAV ETFWHGGSGV VVLPCGAGKT LVGAGAMARS RTTTLILVTN TVSARQWREE
LVRRTTLTED EIGEYSGARK DVRPVTIATY QVLTTRRKGV YTHLELLDAH DWGLIVYDEV
HLLPAPIFRM TADLQARRRL GLTATLVRED GREDEVFSLI GPKRYDAPWK DIEAQGYIAP
AECVEVRLTL PESDRLVYAT AEPEERYRLA ASAPGKTRVV RQILDRHPGE QTLVIGQYLD
QLDELAESLD APLITGQTSV TERQRLFDAF RAGEIQVLVV SKVANFSIDL PEASVAVQVS
GSFGSRQEEA QRLGRLMRPK ADGKTAHFYA VIARDTVDQD FAAHRQRFLA EQGYAYTIVD
AEDLASA
//
