ID A0A2A9ENG8_9MICO Unreviewed; 1522 AA.
AC A0A2A9ENG8;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Murein biosynthesis integral membrane protein MurJ {ECO:0000313|EMBL:PFG39795.1};
GN ORFNames=ATJ97_2311 {ECO:0000313|EMBL:PFG39795.1};
OS Georgenia soli.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Bogoriellaceae;
OC Georgenia.
OX NCBI_TaxID=638953 {ECO:0000313|EMBL:PFG39795.1, ECO:0000313|Proteomes:UP000222106};
RN [1] {ECO:0000313|EMBL:PFG39795.1, ECO:0000313|Proteomes:UP000222106}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21838 {ECO:0000313|EMBL:PFG39795.1,
RC ECO:0000313|Proteomes:UP000222106};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PFG39795.1}.
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DR EMBL; PDJI01000004; PFG39795.1; -; Genomic_DNA.
DR Proteomes; UP000222106; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR CDD; cd13123; MATE_MurJ_like; 1.
DR CDD; cd13973; PK_MviN-like; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR004268; MurJ.
DR NCBIfam; TIGR01695; murJ_mviN; 1.
DR PANTHER; PTHR47019; LIPID II FLIPPASE MURJ; 1.
DR PANTHER; PTHR47019:SF1; LIPID II FLIPPASE MURJ; 1.
DR Pfam; PF03023; MurJ; 1.
DR PRINTS; PR01806; VIRFACTRMVIN.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cell shape {ECO:0000256|ARBA:ARBA00022960};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Peptidoglycan synthesis {ECO:0000256|ARBA:ARBA00022984};
KW Reference proteome {ECO:0000313|Proteomes:UP000222106};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 58..77
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 97..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..149
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 170..192
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 204..226
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 250..275
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 295..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 335..362
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 374..394
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 406..428
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 434..454
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 475..493
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 499..521
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1320..1341
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 570..715
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 955..1008
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1055..1078
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1103..1186
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1228..1251
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1268..1300
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1343..1412
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 687..715
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 955..980
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1113..1142
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1229..1243
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1352..1379
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1522 AA; 153598 MW; C6CD9C362D078D1A CRC64;
MSAARRRGVA GSSAVMFAGT LVSRVLGMVK SPLLLGAAIG INFGAANAFS VANKLPNLIY
MLIAGGVLNA VLVPQIVRAI RNDADRGQAY VNRLLTLAMV GLGSVTVLLT LAAPLLVSLY
AVNLPQEWYD VAVSFGYWCI PQLFFYGMYT LLGQVLNARE IFGPYMWAPA LNNVVAILGL
GAYLVVFGGT AAADDASAWT TSRVALLAGT ATLGIVAQAV VLLVPLHRSG FRYRPQWGLR
GSGLGKASRM AMWVFAALAA NQAAYVVVSN AAAYAFRAGG GARDVAGNGA YDTAFLIYTL
PTSLVTVSLV TALFTRMSSK AAAADLRAVR ADLSVGLRTV SVFTVFATGA LMVLALPVVR
IIAATVTYAE VQSIANVVVA MLGGLVAVGV FTMCQRVYYA FEDARGLFRL QIPMILVLAA
GAAASMLLPP RWTVVGIGVA MTLSNWIGAL VTYLGLRQHL RTIDGGRVLR THLRLVLAAV
PSTLVGWGLL HLLGVDSGLG IFGALWRIAV VGTVMGVLYV VALRRLRVDE LDTLARPVGK
VLVAVGRRAP APVGGMLVRA GAALAPAAVA TTRSGGPDDH DGGPGGGPDG GPAGGPGGGP
GGGPVGGPDG GPAGGPGGGP GCGSDSGSGR GPEGGPGGPG RSSGGGPGDT SVPDTGSPVP
APVAAAENVT VPPVGAAAGD PVRTLGHDAR TGAEHDADKG STALEARTDD AGRGTRHVLD
ERYELGAALE TTVGGVDRRR AHDTILDRPV EALVLPPAGS GVADVLDAAR RAALVEDHRL
AQVLDVGSDG TSAYVVTDPV TGPSLAELTA HGPLEAEQAR AVIGEATSAL ESARRHGVRH
LALRPEALHV TPDGEVLITG LGTDAVLLGL ADPDGSPLAA TRRDATDLVR LLYLCLTGLW
PAVDEEPPAP RSLNPEVPGD LDELCTRTLV DNDGPRSTGE LIRLLAPWPD VDAASVLGPP
PAPPSAAPAP SAPPAAEPAE GAPAPGSSRT GEAPSAGPAG NGGSTGAGAA AAVATGAAGA
AGAAVAGSTV AGAAAGTEQA GGHRLVPTWA RVHADPEPVT DPAAAAPPAP MNDPTATAPL
DAVTAVDPDA VDDAAVTVAG PATAVQPTAG GPDAGPAPAP PSTDPAAVVG PPPPPPVVPS
SAPAPAGTAA LPLQAATDRP ATAPGPRTLS WTPKRPASPA QPPGFPQILD VTDADRATPS
SRHTKNPGAL AGLAVIAGSA VESLKQGARK AAEGTKEGAR KAAEGTRTAA AATRETVGSA
VVAGKEKVAE AGEARRSRPE TAPIPTQQVP VRPSYDDDSL SAVDGPEVPF AERRINPTPV
VLVAVAALVL VLFLVATRTL LAPPEPVSLP RNNPAPTASA EPTPTAEPTP EQSATTQEPA
AGPPLIASLA PLDPEGDGGE NPDLASRAMD GDPATYWRSR SYVNPEYGMK TGIGLAVTLQ
QPATVSSVEI DLRGTGGLVQ IRSTSPETPT EGDVLAEGEM GPGTVFRFDP VETESLVLWF
PRLPTAESDG KNRIELAEVR VG
//
