ID A0A2A9ERT1_9MICO Unreviewed; 814 AA.
AC A0A2A9ERT1;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE SubName: Full=Competence protein ComEC {ECO:0000313|EMBL:PFG41251.1};
GN ORFNames=ATJ97_3799 {ECO:0000313|EMBL:PFG41251.1};
OS Georgenia soli.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Bogoriellaceae;
OC Georgenia.
OX NCBI_TaxID=638953 {ECO:0000313|EMBL:PFG41251.1, ECO:0000313|Proteomes:UP000222106};
RN [1] {ECO:0000313|EMBL:PFG41251.1, ECO:0000313|Proteomes:UP000222106}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21838 {ECO:0000313|EMBL:PFG41251.1,
RC ECO:0000313|Proteomes:UP000222106};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PFG41251.1}.
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DR EMBL; PDJI01000004; PFG41251.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A9ERT1; -.
DR OrthoDB; 7177610at2; -.
DR Proteomes; UP000222106; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000222106};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 36..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 79..100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 267..289
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 296..312
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 318..334
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 341..358
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 364..382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 394..422
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 428..450
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 457..476
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 488..507
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 514..532
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 559..737
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 814 AA; 82355 MW; ADF48D0875F9E75A CRC64;
MPPAPLDARL VPAALVAWAA VHVAVAQPAG WSVAAAAVVL SLAVVPVHLL LRERRAVRRA
GTRPGGAARR RHRDVAHRSP AAAALLTVMV VAAVLSSTAA QVHARTEGVL GDLVAHGASA
MVTGRVAAEP RAMASREWDT TERYRVVVDA AEVTGRGARS AARAPVVVLG PASWGELTLG
DQVEVRGSLV ATDPGDEAVG LLLTSRDPRV VGPPPWHLRA VNLLRGALRA VTADLSPQAR
GLVPGIAVGD DRDLPEDLRT DMRAVSLTHL TAVSGAHVAI LLGAVLGAAV WLPRRARTAV
GAVALVAFVA LVRPEPSVLR SAVMGAVVLL ALVLGRPARA LPALCAAVVA LLLVDPWLAR
SYGFALSVLA TAGLVLLARP WARWLSGVLP RWLATAIAVP AAAQAACGPV VVLLTPALSL
YAVPANLLAA PAVPPATVLG VGATVVAPWW PDAAKALATA ASWFTAWIAL VARALAGAPG
AQLAWPGGTG GALALAAVTA VGIALLARAG PRRTGHVLPV AAVAVVLLVL PGPRQAVTGM
LPDGWPPREW VAIQCDVGQG AAFLVRSGPA AAVMVDVGPA GAGADVCLRD AGVASVDLLV
LTHGHADHVG ALPEVLASVE VRRVLLGPGP EPGGAVEAVL GQLAAARVPV DRPVVGDTTV
RGRAGDVAWE VLGPGADAVG VAAGDAAVND LSLVVSLEAP GLRALALGDV ELDGQARLAR
RLRAAPVAPY DVVVMAHHGS ARQDERLAAL LAPRLTLVSV GQDNDYGHPS TSAVDLYAAS
GPVLRTDLCG QVAVLRTDEA AGLATLAGCP AGSG
//
