ID A0A2A9F0C1_9MICO Unreviewed; 378 AA.
AC A0A2A9F0C1;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Dolichol-phosphate mannosyltransferase {ECO:0000313|EMBL:PFG44236.1};
GN ORFNames=ATJ88_2955 {ECO:0000313|EMBL:PFG44236.1};
OS Isoptericola jiangsuensis.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales;
OC Promicromonosporaceae; Isoptericola.
OX NCBI_TaxID=548579 {ECO:0000313|EMBL:PFG44236.1, ECO:0000313|Proteomes:UP000224130};
RN [1] {ECO:0000313|EMBL:PFG44236.1, ECO:0000313|Proteomes:UP000224130}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21863 {ECO:0000313|EMBL:PFG44236.1,
RC ECO:0000313|Proteomes:UP000224130};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 2 family.
CC {ECO:0000256|ARBA:ARBA00006739}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PFG44236.1}.
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DR EMBL; PDJJ01000001; PFG44236.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2A9F0C1; -.
DR OrthoDB; 9810303at2; -.
DR Proteomes; UP000224130; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004582; F:dolichyl-phosphate beta-D-mannosyltransferase activity; IEA:InterPro.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR CDD; cd06442; DPM1_like; 1.
DR InterPro; IPR039528; DPM1-like.
DR InterPro; IPR001173; Glyco_trans_2-like.
DR InterPro; IPR007267; GtrA_DPMS_TM.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR43398:SF2; DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE; 1.
DR PANTHER; PTHR43398; DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1; 1.
DR Pfam; PF00535; Glycos_transf_2; 1.
DR Pfam; PF04138; GtrA; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000313|EMBL:PFG44236.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:PFG44236.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 233..254
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 260..279
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 300..322
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 334..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 4..168
FT /note="Glycosyltransferase 2-like"
FT /evidence="ECO:0000259|Pfam:PF00535"
FT DOMAIN 236..352
FT /note="GtrA/DPMS transmembrane"
FT /evidence="ECO:0000259|Pfam:PF04138"
SQ SEQUENCE 378 AA; 40908 MW; 961A56E77F5CB783 CRC64;
MDVTVVVPTF NEGANVPELV RRLGLALDGV AAEVLFVDDS RDDTPQVVEE VARTSVVPVR
MIHRERPDGG LSGAVVEGLR SARGERVVVM DGDLQHPPEM VPVLLAAAAD TGVDVVVASR
YTGRGDAGGL DGWHRKAVSK VSGLLARSMF PLRLRNVTDP MTGFFVVRAG AVDAAALRPR
GFKILLEILA RQRLTVAEVP FVFGRRFAGT SKADVRNGTR YLMQLASLRF GRLSPFALIG
ASGAVANLVI LAVLQQLGVH YLPAAVAANV LTIVGNFLLQ ERFVFGDLRA EGRFGVWGRF
AQSFAFNGTE ALVRTVFLWW IVERAVPHPE LVQAGLILVA FMLRYVFLAQ VVYRPRRTGR
SSVSAPDELG VDGTRASS
//
